Motomura H, Akimoto K, Shingo Yamazaki S, Exploratory Profiling of ABC-Family Genes Identifies a Candidate Score in Pediatric Neuroblastoma, CANCER GENOMICS & PROTEOMICS, in press. 2026.
Akimoto K, Tamori S, and Sato K, Mutual Information-based Prognostic Biomarker Discovery in Cancer Genomics: Conceptual Framework and Representative Applications of MI-POG, CANCER GENOMICS & PROTEOMICS, 23, 880-898, 2026.
Shoma Tamori, Keiko Sato, Kazunori Sasaki, Shigeo Ohno & Kazunori Akimoto, An information-theoretic framework identifies tumor dormancy–associated gene signatures for very late recurrence in ER-positive breast cancer Breast Cancer Research, 2026.
Ishii H, Nishiyama K, Nakahara A, Tamori S, Ohno S, Sasaki K, Akimoto K, Cell-cell junctio gene signatures as subtype-specific prognostic biomarkers in breast cancer, PLOSOne, 21(6):e0352254, 2026.
YI-FEI YANG, YUN GENG, HUI XU, KAZUNORI AKIMOTO, YUN-WEN ZHENG, YUYUN XIONG and YU-MEI LI, GGT6 as a Prognostic Biomarker and Therapeutic Target in Melanoma Using an Information-theoretical Method, CANCER GENOMICS & PROTEOMICS, 23, 824-840, 2026.
Komeno M, Miyajima R, Miyashita K, Suzuki M, Matoba T, Miwa A, Katsumoto S, Yasumura R, Ko K, Kotani H, Tamori S, Itakura S, Kusamori K, Nishikawa M, Akimoto K, Suda T, Takahashi C, Higashi N, Zhang F, Toida T, Higashi K, Auranofin Suppresses Cancer Cell Invasion by Inhibiting Heparanase-1 Expression via the aPKC-NF-κB Pathway, Int J Mol Sci, 27(13):5646, 2026.
Zhang S, Saeki K, Haeno H，geneSCOPE: gene spatial co-occurrence of pairwise expression, Brief Bioinform. 27(3). May 2026.
Nagaoka KH, Yamashita H, Mashima C, Zhang G, Saito H, Minamide T, Nakatsuru T, Kamata R, Sakai SA, Yamamoto G, Morita TY, Nakai K, Hakozaki Y, Kinoshita K, Takahashi Y, Nakayama I, Kawazoe A, Pulukuri SM, Ishii Y, Haeno H, Kashima Y, Shitara K, Yano T, Saito T, Ohashi A.，Neutrophil-Macrophage Interactions Shape Inflammatory Macrophage Remodeling in Gastric Cancer During Chemo-Immunotherapy, Cancer Sci. 2026 May 21. doi: 10.1111/cas.70384.
Nakatsuru T, Yamashita H, Mashima C, Zhang G, Saito H, Minamide T, Nagaoka KH, Kamata R, Sakai SA, Yamamoto G, Morita TY, Nakai K, Hakozaki Y, Kinoshita K, Takahashi Y, Nakayama I, Kawazoe A, Ishii Y, Pulukuri SM, Haeno H, Kashima Y, Shitara K, Yano T, Saito T, Ohashi A.，A cDC1-NK/T-Malignant Cell Circuit Drives Immunogenic Remodeling Under PD-1 Blockade in Gastric Cancer，Cancer Sci. 2026 May 21. doi: 10.1111/cas.70381.
Masahiro Kojima, Shunichiro Orihara, Keisuke Hanada, Tomohiro Ohigashi, Sample Size Re-Estimation in Blinded Hybrid-Control Design Using Inverse Probability Weighting, Statistics in Medicine, 2026.
Shunichiro Orihara, Shonosuke Sugasawa, Tomohiro Ohigashi, Keita Hirano, Tomoyuki Nakagawa, Masataka Taguri.Nonparametric, Bayesian Adjustment of Unmeasured Confounders in Cox Proportional Hazards Models, Statistics in Medicine, 2026.
野村尚吾, 澤田航太, 大東智洋, 澤本涼, Hybrid control アプローチを用いるランダム化比較試験の計画と解析：外部データが個人レベルデータの場合, 計量生物学, 2026.
Ryoya Tsunoda, Tomohiro Ohigashi, Junichi Hoshino, Yukiko Ito, Kei Nagai, Reiko Okubo, Hirayasu Kai, Chie Saito, Masahide Kondo, Koichi Asahi, Hirokazu Okada, Shoichi Maruyama, Takashi Wada, Ichiei Narita, Naoki Kashihara, Ronald Pisoni, Roberto Pecoits-Filho, Kunihiro Yamagata, the REACH-J collaborators, Kidney and Cardiovascular Outcomes by CKD stage and etiology of CKD: A Randomly Selected Nationwide Prospective Multicenter Cohort Study in Japan (Reach-J Study), American Journal of Nephrology, 2026.
Kunihiro Yamagata, Tomohiro Ohigashi, Chie Saito, Hirayasu Kai, Ryoya Tsunoda, Reiko Okubo, Masahide Kondo, Haruka Ishii, Masami Inuzuka, Kenji Harada, Ichiei Narita, Hirokazu Okada, Takashi Wada, Shoichi Maruyama, Junichi Hoshino, Patient characteristics and treatment efficacy after switching to hypoxia-inducible factor-prolyl hydroxylase inhibitors from erythropoiesis-stimulating agents in non-dialysis-dependent chronic kidney disease patients: the Reach-J CKD cohort study. BMC Nephrology, 2026.
Yeh YH, Hu M, Otsuka K, Alger BM, Nene SS, Wang H, Maezawa S, Namekawa SH, DAXX directs dual modes of H3.4-to-H3.3 histone replacement in the male germline, Genes Dev. 2026 Jun 1;40(11-12):796-804, 2026.
Esparza JM, Kumar RV, Hu M, Munakata Y, Jain S, Sakashita A, Maezawa S, Schultz RM, Namekawa SH, Paternal folate deficiency reveals meiosis as a metabolic sensing window in the male germline, bioRxiv [Preprint]. 2026 Apr 26:2026.04.22.720272.
Ikuyo A, Fuse N, Mori M, Hirayama A, Yamada Y, Nakamura T, Sagi T, Otsuka K, Namekawa SH, Soga T, Hayashi Y, Maezawa S, Folate-dependent one-carbon metabolism controls meiotic and post-meiotic epigenome remodeling in the male germline, bioRxiv [Preprint]. 2026 Apr 28:2026.04.23.720283
Peng Y, Wang S, Shrestha R, Tian X, Zakharchenko E, Maezawa S, Ascencao C, Smolka M, Cohen P, Reddi PP, Namekawa SH, Qiao H, Digital Chromosome Banding Reveals Distinct Spatiotemporal Dynamics and Sexual Dimorphism in Meiotic Silencing, bioRxiv [Preprint]. 2026 Jun 1:2026.05.28.728562.
Harada Y, Sasaki T, Obata-Ninomiya K, Matsuyama T, Ueha S, Shichino S, Watanabe T, Ogawa S, Ki S, Suzuki Y, Ito N, Motomura Y, Ueno H, Ziegler SF, Inoue H, Burrows P, Kim BS, Murphy KM, Kubo M, IL-13 signaling in cDC2 is required for systemic anaphylactic responses.Proceedings of the National Academy of Sciences of the United States of America, 123(28): e2608478123, 2026.
Shuji Ando, Orthogonal decomposition of the anti-symmetry model via the anti-two-ratios-parameter symmetry model for square contingency tables, European Journal of Pure and Applied Mathematics, 19(2), 7771, 2026.
Shuji Ando, Hanna Fijita and Kouji Tahata, Two-dimensional index for measuring deviance from quasi-symmetry corresponding to conditional quasi-symmetry for ordinal square contingency tables, Brazilian Journal of Probability and Statistics, in press, 2026.
Atsushi Kambayashi, Susumu Takeuchi, Yuji Utsuno, Shinichi Kijima, Hiroyuki Yoshida, Yasuhiro Tsume, Physiologically Based Biopharmaceutics Modeling for Accelerated Formulation Design: Current Status, Regulatory Perspectives, and Future Challenges, Journal of Drug Delivery Science and Technology, 2026.
Masaki Iida, Atsushi Kambayashi, Predicting the required water intake for oral drug administration based on drug and formulation properties using physiologically based biopharmaceutics modeling: Immediate-release formulations containing weakly acidic or neutral drugs, Journal of Drug Delivery Science and Technology, 122, 108399, 2026.
Yoshinori Takahashi, Kazuki Matsui, Naoya Matsumura, Atsushi Kambayashi, Impact of gastric mixing and water intake on postprandial pharmacokinetics of orally disintegrating tablets: A PBBM-based study, European Journal of Pharmaceutics and Biopharmaceutics, 226, 115130, 2026.
Urasaki W, Kawamitsu G, Nakagawa T, Tahata K, A measure of departure from symmetry based on the Fisher-Rao distance for contingency tables, Behaviormetrika, 53, 439-458, 2026.
Tabata R, Ohigashi T, Sozu T, Dose optimization design for randomized phase II trials with toxicity and efficacy endpoints, Pharmaceutical Statistics, 25(5): e70112, 2026.
Y. Otani, S. Sawada, H. Ohmura and K. Katsurada, Speech synthesis from real-time MRI articulatory data with precise F0 reproduction, Acoustical Science & Technology, 47 (4), 314-323, 2026
Yuki Ando, Asanao Shimokawa, Application of isolation forest to detect differentially expressed genes in RNA-seq data, Advances and Applications in Statistics, 93(7) (2026), 783-803, 2026.
Kojima K, Li Y, Tomizawa S, Kohara M, Kuze Y, Sato T, Ebata T, Kubiura-Ichimaru M, Cao M, Hattori T, Maezawa S, Winge SB, Almstrup K, Nakaki R, Sato S, Miyagi Y, Daigo Y, Yoshioka T, Hasegawa Y, Kinoshita Y, Hyuga T, Moriya K, Kobayashi H, Baskin L, Sankai T, and Watanabe T, Establishment of DNA methylation during primate germ cell development, Nat Commun, 17(1):4983, 2026.
Yeh Y, Hu M, Otsuka K, Alger BM, Nene SS, Wang H, Maezawa S, and Namekawa SH, DAXX Directs Dual Modes of H3.4-to-H3.3 Histone Replacement in the Male Germline, Genes Dev., 40(11-12):796-804, 2026.
2025 (104 papers)
Suzuki M, Komeno M, Yasumura R, Miwa A, Enomoto M, Kotani H, Matsumoto K, Akimoto K, Takahashi C, Igarashi K, Higashi K, Identification of Inhibitors for eIF5A2-Dependent Translation Elongation by Monitoring the Translational Efficiency of Polyproline Motif in Mitochondrial Fission Regulator 1, Biol Pharm Bull. 49(2):355-363, 2026.
Machida R，Sakamaki K，Ohigashi T，Sozu T，Dynamic prediction of analysis timing in clinical trials using joint models of longitudinal and time-to-event data, Statistics in Medicine, 44:e70312, 2025.
Kubo H, Sozu T, Mitsunaga R, Hazama H, Sekikawa N, Wada R, Watanabe Y, Tamura A, Yamazaki T, Ohta S, Suzuki S, Sugimoto K, Experienced stigma in Japanese outpatients with diabetes: Age and polypharmacy matter, Medicine. 105(12): e47960, 2026.
Hamaji M，Miyamoto S，Sozu T，Ohsumi A，Kobayashi M，Nakagawa T，Sonobe M，Aoyama A，Ishikawa M，Sakai H，Miyahara R，Menju T，Date H，Chen-Yoshikawa TF , Pre-weekend effect in pulmonary resection for non-small cell lung cancer: a multicenter retrospective cohort study, Surgery Today, 56:2042–2049, 2025.
Negishi H, Hirata K, Aiyama H, Fujita K, Komatsu Y, Kato N, Shibata Y, Tsuda K, Yamazaki T, Sato M, Watanabe S, Sugii N, Konishi T, Bryan J. Mathis, Ohigashi T, Endo M, Ishikawa E, Matsumaru Y, Triple-Drug Therapy with Goreisan, Tranexamic Acid and Carbazochrome Sodium Sulfonate Hydrate to Prevent Recurrence after Chronic Subdural Haematoma Surgery: A Multicentre, Randomised, Controlled Trial Protocol, BMJ Open, 2025.
Takuya Yoshimoto, Satoru Shinoda, Kouji Yamamoto and Kouji Tahata, Optimal Bayesian predictive probability for delayed response in single-arm clinical trials with binary efficacy outcome, Communications in Statistics - Theory and Methods, 55(6), 1687–1704, 2025.
Keita Nakamura, Tomoyuki Nakagawa, and Kouji Tahata, Quasi-symmetry and geometric marginal homogeneity: a simplicial approach to square contingency tables, InformationGeometry, 1-25, 2025.
Wataru Urasaki, Tomoyuki Nakagawa, Jun Tsuchida and Kouji Tahata, Visualization for Departures from Symmetry with the Power-Divergence-Type Measure in Square Contingency Tables, Psychometrika, 90(5):1887-1906, 2025.
Hisaya Okahara and Kouji Tahata, Modeling asymmetry in multi-way contingency tables with ordinal categories via f-divergence, Statistical Papers, 67, 3, 2026.
Takikawa M, Nakano A, Krishnaraj J, Tabata Y, Watanabe Y, Okabe A, Sakaguchi Y, Fujiki R, Mochizuki A, Tajima T, Sada A, Matsushita S, Wakabayashi Y, Araki K, Kaneda A, Ishikawa F, Sadaie M, and Ohki R, Extrinsic induction of apoptosis and tumor suppression via the p53-Reprimo-Hippo-YAP/TAZ-p73 pathway, Proc. Natl. Acad. Sci. USA, 122, e2413126122, 2025.
Aisa Suzuki, Tsukasa Shigehiro, Mayumi Hirakawa, Risa Hirano, Minori Tamai, Koshi Akahane, Kazuo Okamoto, Hiroshi Takayanagi, Yuya Terashima, Satoshi Ueha, Toshimori Kitami, Masatoshi Takagi, Dai Keino, Keisuke Kato, Hiroshi Kawaguchi, Moeko Hino, Akihiko Yoshimura, Takeshi Inukai, and Tomokatsu Ikawa, Self-reinforcing IL-1β signaling accelerates the development and recurrence of TCF3::HLF-positive B-ALL, Blood, 147, 21, 2026.
Yui Miyatake, Takeshi Kamakura, Tomokatsu Ikawa, Ryo Yanagiya, Ryutaro Kotaki, Kazuaki Kameda, Ryo Koyama-Nasu R, Kazuki Okuyama, Ken-Ichiro Hirano, Hiroyuki Hosokawa, Katsuro Hozumi, Masato Ohtsuka, Takahiro Kishikawa, Chikako Shibata, Motoyuki Otsuka, Reo Maruyama, Kiyoyuki Ando, Tomohiro Kurosaki, Hiroshi Kawamoto, and Ai Kotani, A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency, eLife. 13:RP101510, 2026.
Porfirio de la Cruz-Cruz, Mauricio A. García, José Trinidad Pérez-Urizar, Bertil Abrahamsson, Rodrigo Cristofoletti, Atsushi Kambayashi, Mehul Mehta, Alan Parr, James E. Polli, Vinod P Shah, Naseem Charoo, Sirajunisa Talath, Jennifer Dressman, Peter Langguth, Biowaiver monograph for immediate-release solid oral dosage forms: Amlodipine besylate, Journal of Pharmaceutical Sciences, 115(2):104108, 2026.
Kitamura Y, Takahashi K, Maezawa S, Munakata Y, Sakashita A, Katz SP, Kaplan N, Namekawa SH, CTCF-mediated 3D chromatin sets up the gene expression program in the male germline. Nat Struct Mol Biol. 2025 Jul;32(7):1227-1240, 2025.
Yi C, Kitamura Y, Maezawa S, Namekawa SH, Cairns BR, ZBTB16/PLZF regulates juvenile spermatogonial stem cell development through an extensive transcription factor poising network. Nat Struct Mol Biol. 2025 Jul;32(7):1213-1226, 2025.
Takato Fukugami and Tomofumi Matsuzawa, An implementation of routing in wireless mesh networks using the maximum flow problem, IEICE Communications Express, 14(7):275-278, 2025.
Masaki Shimono, Kaiyu Suzuki, Masahiro Kobayashi, Shigeo Akashi and Tomofumi Matsuzawa, Performance measurement of Bayesian online changepoint detection and its application, Proc. SPIE 13815,Second International Conference on Advanced Robotics, Automation Engineering, and Machine Learning, 13815, 83-103, 2025.
Shigeo Akashi and Tomofumi Matsuzawa, Application of multiuser listening system to virtual remote surveillance system, Proc. SPIE 13815, Second International Conference on Advanced Robotics, Automation Engineering, and Machine Learning, 13815, 104-113, 2025.
Masaki Miyata and Tomofumi Matsuzawa, Co-Design of Battery-Aware UAV Mobility and Extended PRoPHET Routing for Reliable DTN-Based FANETs in Disaster Areas, Electronics, 15(3),591, 1-17, 2026.
Kaoru Takabatake and Tomofumi Matsuzawa, FANET Routing Protocol for Prioritizing Data Transmission to the Ground Station, Network, 6(1), 7, 1-22, 2026.
Satoshi Arakawa, Kaiyu Suzuki and Tomofumi Matsuzawa, Geolocalization of Unmanned Aerial Vehicle Images and Mapping onto Satellite Images Utilizing 3D Gaussian Splatting, Sensors, 26(4), 1-21, 2026.
Rentaro Wakayama, Tomotaka Momozaki and Shuji Ando, Improving maximum tolerated dose selection in model-assisted designs for phase I trials through Bayesian dose–response model, Pharmaceutical Statistics, 24(6):e70046, 2025.
Shuji Ando, Anti-linear-diagonals-parameter symmetry model and orthogonal decomposition of anti-symmetry for square contingency tables with ordinal classifications, European Journal of Pure and Applied Mathematics, 18(4), 6439, 2025.
Takuto Iijima, Tomotaka Momozaki and Shuji Ando, On window mean survival time with interval-censored data, Statistics in Medicine, 45(6-7):e70491, 2026.
Ayaka Yagi, Takashi Seo, Tests for one and two mean vectors and simultaneous confidence intervals with monotone incomplete data, Communications in Statistics–Simulation and Computation, 54, 10, 4403-4430, 2025.
Eri Kurita, Zofia Hanusz, Takashi Seo, A modified normalizing transformation statistic based on kurtosis testing multivariate normality, International Journal of Statistics and Probability, 14(4), 1-34, 2025.
Shitara Y, Maeda-Minami A, Ishikawa H, Mutoh M, Mano Y , Epidemiologic survey of ulcerative colitis and crohn’s disease in Japan using claim data, Scientific Reports, 16, 5158, 2026.
Satoka Kasai, Saki Ukai, Junpei Kuroda, Tsugumi Yamauchi, Daisuke Yamada, Akiyoshi Saitoh, Satoshi Iriyama, Masashi Suzuki, Kazuki Arita, Yoshio Nakano, Satoru Miyazaki, Kazumi Yoshizawa, Pain-stimulated ultrasound vocalizations and their impact on pain response in mice, PLoS One, 20(7): e0324730, 2025.
Tsugumi Yamauchi, Kou Takahashi, Toshinori Yoshioka, Daisuke Yamada, Yoshio Nakano, Satoka Kasai, Satoshi Iriyama, Kazumi Yoshizawa, Shoichi Nishino, Satoru Miyazaki, Akiyoshi Saitoh, Inaudible airborne ultrasound affects emotional states in the olfactory bulbectomized rat depression model, Sci Rep. 15(1): e3199, 2025.
Toshinori Yoshioka, Sayaka Kimiki, Mayuna Yamazaki, Takumi Hamano, Mizuki Ou, Yumi Ode, Rui Ehara, Keita Kajino, Satoka Kasai, Kazumi Yoshizawa, Tsuyoshi Saitoh, Daisuke Yamada, Hiroshi Nagase, Akiyoshi Saitoh, Agonists of the opioid δ-receptor improve irritable bowel syndrome-like symptoms via the central nervous system. Br J Pharmacol, 182(7):1599-1609, 2025.
Tomo Nakazawa, Tsutomu Kumazawa, Yasushi Kambayashi, Munehiro Takimoto, Effectiveness of Sub-MSH Size Pruning in BCP Based ILP, Proceedings of the 18th ACM International Conference on PErvasive Technologies Related to Assistive Environments (PETRA '25), 435 - 438, 2025.
Asaka Takase, Tsutomu Kumazawa, Munehiro Takimoto, Gravitational Search Algorithm-Based Efficient Model Checking, Proceedings of the 18th ACM International Conference on PErvasive Technologies Related to Assistive Environments (PETRA '25), 468 - 472, 2025.
Ayane Takahashi, Soichiro Fujimura, Genki Kudo, Shunsuke Hataoka, Gota Nagayama, Mitsuyoshi Watanabe, Yuichi Sasaki, Hiroyuki Enomoto, Hiroyuki Nishiyama, Hayato Ohwada, Toshihiro Ishibashi and Yuichi Murayama, Woven EndoBridge Device Size Prediction Using Machine Learning with Intracranial Aneurysm Morphological Features, Proceedings of the Joint Symposium of Thirty-First International Symposium on Artificial Life and Robotics (AROB 31st 2026), 647-652, 2026.
Ryosuke Minami, Ryo Hatano and Hiroyuki Nishiyama, Comparison of Dimensionality Reduction Methods for MCI Classification Using Machine Learning and Static Functional Connectivity Based on Resting-State Functional Magnetic Resonance Imaging, Proceedings of the 18th International Conference on Agents and Artificial Intelligence (ICAART2026), 4, 3063 – 3070, 2026.
Kaede Tsuda, Yoko Ogino, Akira Sato, Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly (ADP-ribose) glycohydrolase inhibitor. FEBS Open Bio, 16(5):1020–1029, 2025.
Yuxi Yang, Masayuki Sakurai, Advances in Detection Methods for A-to-I RNA Editing, WIREs RNA, 16: e70014, 2025.
Yuxi Yang, Mai Kubota, Kokone Hasegawa, Chao Zeng, Kazuko Nishikura, Michiaki Hamada, Masayuki Sakurai, Mitotic phosphorylation of ADAR1 regulates its centromeric localization and is required for faithful mitotic progression, bioRxiv (in revision in iScience), 2025
Otani Y, Kawarai M, Kobayashi M, Nozaki Y, Uchida R, Tezuka K, Yokoyama M, Mizunoe Y, Narita T, Haeno H, Miyano K, Uezono Y, Higami Y, Identification of a novel MIPEP splice variant with altered substrate-binding properties, Biochem Biophys Rep, 44:102329, 2025.
Shu Sekiya, Rei Tanaka, Hisashi Iijima, Yoshio Nakano, Satoru Miyazaki, Atsushi Toyomi, Hajime Hashiba, Masanori Nagatsu, Yoshiaki Shikamura, Prevention of Serious Adverse Drug Reactions and Economic Effects Through Community Pharmacists’ Inquiries, Home Care, and Medication Follow-up: From The Japanese Nationwide Pharmacy Collaboration Survey in 2023, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2025.
Hirai K, Ishii T, Eom H, Takado R, Higashi K, Iwasaki Y, Ito R, Higashi N, Akiyama H, Development of a liquid chromatography–tandem mass spectrometry method for 4-aminobenzoic acid ethyl ester–derivatized glycosaminoglycans and its application to synovial fluid, J. Chromatogr. Open, 9, 100324, 2026.
Tang R, Aizemaiti A, Tamemoto Y, Kume R, Yasuda K, Sato K, Abo H, Tsuji K, Higashi K, Kiyoshi M, Hashii N, Ishii-Watabe A, Kawashima H, Hatakeyama H. Antibody therapeutics with high affinity for FcγRs exacerbate anaphylaxis via FcγR-mediated capture by tumor-associated myeloid cells, J. Immunother. Cancer, 14, e013316, 2026.
Nishiguchi H, Nakamura K, Arai R, Hamajima R, Abe H, Ishida A, Tokeshi M, Higashi K, Saitoh A, Takahashi H, Structural Elucidation of Azo and Quinoneimine Products Formed in Diazonium-Based Color Reactions of Cannabinoids, Molecules, 31, 796, 2026.
Shi J, Nakamura M, Baba R, Arakawa S, Yamaguchi A, Hariya T, Suzuki R, Inazuki Y, Takahashi K, Tsuiji M, Oku T, Komine M, Shimekake M, Higashi K, Nakamura M, Sasaki K, Nakajima M, Irimura T, Higashi N, A Novel Chimeric Molecule of Heparanase and Ig-Fc Enables Histochemical and Cytochemical Detection of O-sulfated Heparan Sulfate, Int. J. Mol. Sci., 26, 11293, 2025.
Nakamura K, Nishiguchi H, Arai R, Hamajima R, Abe H, Ishida A, Tokeshi M, Higashi K, Saitoh A, Takahashi H, Isolating and Determining the Structures of Colored Products from the Reactions of Cannabinoids with Fast Blue RR, Molecules, 30, 3462, 2025.
Adrienne Y L Chan, Shahram Bahmanyar, Kebede Beyene, Greta Bushnell, Bruce Carleton, Amy Hai Yan Chan, Sharon Cook, Stephen Crystal, Kari Furu, Svetla Gadzhanova, Patricia García Poza, Rosa Gini, Sabrina Giometto, Jeff Harrison, Ulrike Haug, Christine Hsu, Harpa Lind Hjördísar Jónsdóttir, Joe Kai, Øystein Karlstad, Ju Hwan Kim, Kiyoshi Kubota, Edward Chia-Cheng Lai, Hyesung Lee, Wallis C Y Lau, Kathy H Li, Ersilia Lucenteforte, Géric Maura, Anke Neumann, Virginia Pate, Anton Pottegård, Nadeem Qureshi, Lotte Rasmussen, Johan Reutfors, Elizabeth E Roughead, Leena Saastamoinen, Tsugumichi Sato, Oliver Scholle, C C M Schuiling-Veninga, Chin-Yao Shen, Ju-Young Shin, Til Stürmer, Katja Taxis, Marco Tuccori, Stephen Weng, Kirstie H T W Wong, Helga Zoega, Kenneth K C Man, Ian C K Wong, International Trends in Opioid Prescribing by Age and Sex from 2001 to 2019: An Observational Study Using Population-Based Databases from 18 Countries and One Special Administrative Region, CNS DRUGS, 39(11):1173–1185, 2025.
Chengsheng Ju, Kiyoshi Kubota, Xi Xiong, Tsugumichi Sato, Camille Carroll, Anette Schrage, Li Wei, Thomas Foltynie, Long-term outcomes associated with istradefylline versus catechol-O-methyltransferase inhibitors in patients with Parkinson's disease: a nationwide real-world cohort study, PARKINSONISM & RELATED DISORDERS, 144:108211, 2026.
Xu P, Ueha S, Aoki H, Kitabatake M, Chen M, Shichino S, Hara A, Ouji-Sageshima N, Ito T, Motozono C, Matsushima K, Repeated mRNA vaccination and breakthrough infection reveal durable dominance but diminishing recall of vaccine-induced CD8⁺ T-cell clones, International Immunology, dxag004, 2026.
Wu B, Shichino S, Ueha S, Matsukiyo R, Ishimura Y, Ogiwara H, Takasu M, Yamano S, Umeda Y, Matsushima K, Ex vivo lung-organoid model for aberrant basaloid cell induction and activation, Inflamm Regen., 45(1):33, 2025.
Takahashi M, Tsunoda M, Aoki H, Kurosu M, Ogiwara H, Shichino S, Bending D, Ishikawa S, Thaventhiran JED, Matsushima K, Ueha S, A pan-immunotherapy signature to predict intratumoral CD8+ T cell expansions, Nat Commun, 16(1):9175, 2025.
Shirai Y, Enomoto T, Takeda Y, Edahiro R, Takahashi-Itoh M, Noda Y, Adachi Y, Nakayama M, Kawasaki T, Koba T, Futami Y, Yoshimura H, Amiya S, Hara R, Yamamoto M, Nakatsubo D, Suga Y, Naito M, Masuhiro K, Matsuki T, Hirata H, Iwahori K, Nagatomo I, Miyake K, Koyama S, Fukushima K, Shiroyama T, Naito Y, Futami S, Natsume-Kitatani Y, Ose N, Funaki S, Nojima S, Shichino S, Yanagawa M, Shintani Y, Nogami-Itoh M, Adachi J, Inoue Y, Tomonaga T, Okada Y, Mizuguchi K, Kumanogoh A, Serum vesicle biomarkers reflect the disease activity of idiopathic pulmonary fibrosis, J Trans Med. 23(1):1102, 2025.
Matsumoto N, Ueha S, Ueha R, Koyama M, Yamakawa K, Sato T, Goto T, Kono T, Shichino S, Matsushima K, Kondo K, HPV6-Induced Gene Expression Signature in Recurrent Respiratory Papillomatosis, Laryngoscope. 135(10):3732-3739, 2025.
Zong C, Sato H, Schneider B, Shichino S, Ueha S, Wu B, Matsushima K, Okayama T, Ikeo K, Urushitani M, Ito H, Iwama S, Fergany A, Ichihara S, Ohsako S, Ichihara G, Acrylamide-induced noradrenergic axon degeneration is promoted via a non-cell autonomous mechanism, involving microglial Tnfaip2/TNF-α and oxidative stress pathways, J Hazard Mater. 496:139125, 2025.
Niitsu T, Kataoka T, Fukushima K, Motooka D, Shichino S, Natsume-Kitatani Y, Kitamura H, Niwa T, Baba T, Okuzaki D, Kumanogoh A, Akira S, Okudela K, Ogura T, Spatial transcriptomics identifies SPARC as a prognostic marker in interstitial lung diseases, J Pathol. 267(1):79-91, 2025.
Matsui H, Nagamachi A, Koizumi M, Kudo R, Ajiro M, Harada H, Harada Y, Shichino S, Yoshimi A, Genotype-integrated single-cell transcriptome analysis reveals the role of DDX41 pR525H in a patient with myelodysplastic neoplasms, Sci Rep. 15(1):22849, 2025.
Enomoto T, Takeda Y, Shirai Y, Hasegawa T, Zhao F, Lunding H, Pohl M, Edahiro R, Shichino S, Kawasaki T, Yoshimura H, Hara R, Amiya S, Yamamoto M, Nakatsubo D, Tanizaki S, Nakayama M, Noda Y, Niitsu T, Adachi Y, Tone M, Abe Y, Naito M, Masuhiro K, Naito Y, Shiroyama T, Miyake K, Koyama S, Fukushima K, Iwahori K, Hirata H,Nagatomo I, Nojima S, Yanagawa M, Inoue Y, Kumanogoh A, Serum C-C motif chemokine ligand 17 as a predictive biomarker for the progression of non-idiopathic pulmonary fibrosis interstitial lung disease, Respir Res. 26(1):157, 2025.
Kohda H, Tanaka M, Shichino S, Arakawa S, Komori T, Ito A, Wada E, Ochi K, Yuan X, Takeda T, Saiki A, Tatsuno I, Ikeda K, Miyai Y, Enomoto A, Morikawa Y, Shimizu S, Ueha S, Matsushima K, Ogawa Y, Suganami T, Novel cell-to-cell communications between macrophages and fibroblasts regulate obesity-induced adipose tissue fibrosis, Diabetes, 74(7):1135-1152, 2025.
Qiu Y, Tang XX, Shichino S, Kushwaha PP, Sanders YY, Russo RC, Mo C, Editorial: Cellular and molecular mechanisms of lung regeneration, repair, and fibrosis, volume II, Front Cell Dev Biol. 13:1653034, 2025.
Nagashima Y, Ogino M, Okiyama R, Chiwaki R, Ishii H, Nohata K, Nakahara A, Ozaki A, Kasai T, Tamori S, Ohno S, Sasaki K, Akimoto K. Co-expression of PKCζ and ALDH1A3 Is Associated With Poor Chemotherapeutic Responses in Basal-like Breast Cancer. CANCER GENOMICS & PROTEOMICS, 23, 322-341, 2025.
Tamori S, Matsuda C, Kasai T, Ohno S, Sasaki K, Akimoto K. Asymmetric cell division of ALDH1-positive cancer stem cells generates glycolytic metabolically diverse cell populations, Sci Rep. 15(1):13932, 2025.
Suzuki M, Suzuki T, Nakano Y, Matsumoto K, Manaka H, Komeno M, Tamori S, Sato A, Dohmae N, Akimoto K, Miyazaki S, Suda T, Toida T, Kashiwagi K, Igarashi K, Higashi K. Polyamines stimulate the protein synthesis of the translation initiation factor eIF5A2, participating in mRNA decoding, distinct from eIF5A1, J Biol Chem. 301(8):110453, 2025.
Nagashima Y, Sasaki K, Chiwaki R, Ishii H, Nohata K, Maemura Y, Kasai T, Ozaki A, Tamori S, Ohno S, Akimoto K. High Expression of PKCζ And CTNNBIP1 Is Associated With Poor Prognosis in Luminal B Breast Cancer, Cancer Genomics Proteomics. 22(4):538-556, 2025.
Nagashima Y, Sasaki K, Nohata K, Chiwaki R, Maemura Y, Kasai T, Ozaki A, Tamori S, Ohno S, Akimoto K. High Expression of PKCζ and ALDH1A3 Is Associated With Poor Prognosis in Luminal B Breast Cance, Anticancer Res., 45(10):4357-4372, 2025.
Maemura Y, Ozaki A, Chiwaki R, Enomoto M, Tada Y, Nagashima Y, Ishii H, Nohata K, Kasai T, Okiyama R, Harada Y, Tamori S, Ohno S, Sasaki K, Akimoto K, High p62 and ALDH1A3 reduce the effectiveness of endocrine therapy in luminal B breast cancer, Cancer Diagn Progn.5(6):677-697 2025.
Nohata K, Enomoto M, Ishiyama A, Nagashima Y, Okiyama R, Kasai T, Tamori S, Harada Y, Ohno S, Sasaki K, Akimoto K, PKCζ, CTNNBIP1 and ALDH1A3 expression in luminal B breast cancer indicates decreased hormone therapyeffectiveness, Cancer Diagn Progn. 5(6):706-719 2025.
Takahashi M, Aoyama A, Hamaji M, Sozu T, Kobayashi M, Nakagawa T, Ishikawa M, Miyahara R, Huang CL, Fujinaga T, Sakai H, Katakura H, Sonobe M, Okumura N, Kayawake H, Menju T, Miyamoto E, Miyata R, Okada H, Kono T, Sumitomo R, Date N, Fukada T, Matsumoto A, Sakaguchi Y, Date H. Clinical significance of the preoperative prognostic nutritional index in patients with resectable non-small cell lung cancer: a multicenter study. Surgery Today 2025; 55(7):918-929, 2025.
Ohigashi T, Maruo K, Sozu T, Gosho M. Nonparametric Bayesian approach for dynamic borrowing of historical control data. Biometrics.81, ujaf118, 2025.
Hayashi H, Ito S, Fukuda H, Sata M, Abe Y, Fujimoto K, Fukuda D, Hanajima Y, Horii M, Ikehara N, Inoko M, Izumi C, Izumiya Y, Nakayama T, Sozu T, Toyoda S, Watanabe M, Yokoi M, Kitakaze M. Rationale and design of an exploratory, randomized, open-label, multicenter clinical trial to investigate the efficacy of long-acting β2-agonist/long-acting muscarinic antagonist on heart failure complicated by chronic obstructive pulmonary disease (COPD-HF Trial). Circulation Reports 2025 7(5):383-388.
Ohigashi T, Maruo K, Sozu T, Sawamoto R, Gosho M. Potential bias models with Bayesian shrinkage priors for dynamic borrowing of multiple historical control data. Pharmaceutical Statistics. 24, e2453, 2025.
Minewaki S, Ohigashi T, Sozu T. Evaluating marginal likelihood approximations of dose–response relationship models in Bayesian benchmark dose methods for risk assessment. Computational Toxicology. 100347, 2025.
Nakagawa Y, Sozu T. Comparison of parametric and hybrid methods for estimating mean survival time in clinical study. Journal of Biopharmaceutical Statistics. 36(5), 1065-1074, 2025.
Suzuki Y, Suzuki C, Suzuki Y, Kawana F, Ohigashi T, Maruo K, Watanabe T, Abe T. Effects of optimal timed automatic awakening from a short daytime nap on cognitive performance, alertness, and fatigue. Scientific Reports.15, 37228, 2025.
Shimada K, Gosho M, Ohigashi T, Kume K, Yano T, Ishii R, Maruo K, Inokuchi R, Iwagami M, Ueda H, Tanaka M, Sanuki M, Tamiya N. Risk of postoperative pneumonia after extubation with the positive pressure versus normal pressure technique: a single-center retrospective observational study. Journal of Anesthesia.39, 5–14, 2025.
Zeng Q, Tamori S, Harada T, Application of Graph Attention Network for Breast Cancer Data and Explanation of Prediction Basis, IEEE Access, 13, 99183-99191, 2025.
Chan AYL, Bahmanyar S, Beyene K, Bushnell G, Carleton B, Chan AHY, Cook S, Crystal S, Furu K, Gadzhanova S, García Poza P, Gini R, Giometto S, Harrison J, Haug U, Hsu C, Hjördísar Jónsdóttir HL, Kai J, Karlstad Ø, Kim JH, Kubota K, Lai EC, Lee H, Lau WCY, Li KH, Lucenteforte E, Maura G, Neumann A, Pate V, Pottegård A, Qureshi N, Rasmussen L, Reutfors J, Roughead EE, Saastamoinen L, Sato T, Scholle O, Schuiling-Veninga CCM, Shen CY, Shin JY, Stürmer T, Taxis K, Tuccori M, Weng S, Wong KHTW, Zoega H, Man KKC, Wong ICK. International Trends in Opioid Prescribing by Age and Sex from 2001 to 2019: An Observational Study Using Population-Based Databases from 18 Countries and One Special Administrative Region, CNS Drugs. 39(11):1173-1185, 2025.
Teramoto M, Kawasumi K, Furuoka M, Sato T, Maeda-Minami A, Yamamoto Y, Mano Y, Kawasaki T, Nagata M, Kawano Y. Predictors of chemotherapy-related unplanned acute care in outpatients receiving oral anticancer drugs, Sci Rep. 15(1):34774, 2025.
Niino T, Masada T, Takagi T, Kataoka M, Yoshida H, Yamashita S, Kambayashi A. Integrating In Vitro BE Checker with In Silico Physiologically Based Biopharmaceutics Modeling to Predict the Pharmacokinetic Profiles of Oral Drug Products. Pharmaceutics 17(9), 1222, 2025
Ishihara M, Kambayashi A. Physiologically based biopharmaceutics modeling to predict bioequivalence of rivaroxaban formulated as conventional tablets, OD tablets, and fine granules. J Drug Deliv Sci Tech114, 107631, 2025
Negoya R, Tsueoka M, Sun X, Nishida S, Abrahamsson B, Charoo N, Cristofoletti R, Langguth P, Mehta M, Parr A, Polli J, Shah V, Dressman J, Kambayashi A. Biowaiver monograph for immediate-release solid oral dosage forms: Empagliflozin. J Pharm Sci114(12), 104023, 2025
Mizushima R, Shimokawa A, Linear Regression Analysis for Interval-Valued Data, Advances and Applications in Statistics, 92(6), 929-948, 2025.
Uryu H, Saeki K, Haeno H, Kapadia CD, Furudate K, Nangalia J, Chapman MS, Zhao L, Hsu JI, Zhao C, Chen S, Tanaka T, Li Z, Yang H, DiNardo C, Daver N, Pemmaraju N, Jain N, Ravandi F, Zhang J, Song X, Thompson E, Tang H, Little L, Gumbs C, Orlowski RZ, Qazilbash M, Bhalla K, Colla S, Kantarjian H, Shamanna RK, Ramos CB, Nakada D, Futreal PA, Shpall E, Goodell M, Garcia-Manero G, Takahashi K. Clonal evolution of hematopoietic stem cells after myeloma targeting chemotherapy and autologous stem cell transplantation. Nat Genet. 57(7):1695-1707, 2025.
Shoya Iwanami, Toshiko Sato, Hiroshi Haeno, Longchen Xu, Keimyo Imamura, Jun Ooehara, Xun Lan, Hiromitsu Nakauchi, Shingo Iwami, Ryo Yamamoto. Stable platelet production via the bypass pathway explains long-term hematopoietic stem cell reconstitution. iScience. 28(6):112547, 2025.
Mizunoe Y, Kumagai M, Fukai H, Hachiya K, Otani Y, Nozaki Y, Tezuka K, Kobayashi M,Haeno H, Saeki K, Murayama Y, Shimano H, Higami Y. Caloric restriction alters NCOA2 splicing to regulate lipid metabolism in subcutaneous white adipose tissue. Biochem Biophys Res Commun. 765:151871. 2025.
Nakamura M, Kageyama SI, Hirata H, Ohira M, Sakai SA, Hakozaki Y, Hojo H, Fujisawa T, Yamashita R, Haeno H, Kanai A, Suzuki Y, Yamaguchi M, Tsuchihara K, Zenda S. Tumor-Agnostic Circulating Tumor DNA Analysis as a Comprehensive Predictive Biomarker of Recurrence after Ablative Radiotherapy for Early-Stage Non-Small Cell Lung Cancer. Clin Lung Cancer. S1525-7304(25)00238-4, 2025.
Ando S, Anti-diagonals-parameter symmetry model for square contingency tables with ordinal classifications, European Journal of Pure and Applied Mathematics 18, article number 6079, 2025.
Ando S. An index for discriminating the direction of anti-sum-asymmetry for square contingency tables, Biometrical Letters 62, 49-63, 2025.
Toyooka S, Masuda H, Arai N, Osaki Y, Ando S, Kawano, H. and Nakagawa, T. Assessment of intraoperative soft tissue balance in functional alignment total knee arthroplasty: A comparative study with anatomic alignment, Journal of Experimental Orthopaedics 12, article number e70315, 2025.
Ando S. A directional index to measure the degree of asymmetry for square contingency tables, Journal of the Korean Statistical Society, 54, 1251-1268, 2025.
Hosonuma R, Kawasaki T, Seo T, On the Extension Test Statistics for the Sub-mean Vector under Two-step Monotone Missing Data, Sankhya-Series B-Applied and Interdisciplinary Statistics,Online version, 87, 434-467, 2025.
Sumikawa T, Kawasaki T, Seo T, Tests for Profile Analysis in Behrens-Fisher Problem, Technical Report, Statistical Research Group, Hiroshima University, 25, Online version, 3, 2025.
Ryosuke Minami, Ryo Hatano, Hiroyuki Nishiyama: Classification of mild cognitive impairment using machine learning with dynamic functional connectivity from resting-state functional MRI, Proceedings of the 18th ACM International Conference on PErvasive Technologies Related to Assistive Environments (PETRA2025), pp. 458-567, 2025
Maezawa S, Yukawa M, Sakashita A, Barski A, Namekawa SH. Site-specific DNA demethylation during spermatogenesis presets the sites of nucleosome retention in mouse sperm. eLife. 105926, 2025.
Notomi Y, Dobata S, Kazawa T, Maezawa S, Namiki S, Kanzaki R, Haupt SS. Innate visual attraction before, during and after escape from adverse substrates in carpenter ants. J Exp Biol. 228(13):jeb250278. 2025.
Otsuka K, Sakashita A, Maezawa S, Schultz RM, Namekawa SH. KRAB zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution. Genome Res. 35(3):417–31. 2025.
Nakai K, Akter E, Kon S. Basal invasion of cancer cells driven by cell-cell interactions: An affirmative role of cell competition in cancer progression. Cancer Science 116:2340-2346, 2025.
Yoshida N, Maeda-Minami A, Mutoh M, Iwai N, Kobayashi R, Inoue K, Dohi O, Itoh Y, Hirose R, Mano Y, Ishikawa H. The Statuses of Colonoscopy and Colorectal Cancer According to Big National Disasters Such as COVID-19 and Earthquake, Dig Endosc. 37, 1190-1197, 2025.
Yoshida N, Ishikawa H, Mutoh M, Iwai N, Kobayashi R, Inoue K, Hirose R, Dohi O, Itoh Y, Yoda A, Maeda-Minami A, Mano Y. Differences in complications between colonoscopy and esophagogastroduodenoscopy in Japan using large-scale health insurance claims data, Endosc Int Open. 13, a26896049, 2025.
Hagiwara M, Maeda-Minami A, Matano F, Nounaka Y, Murai Y, Morita A, Mano Y. Association between Statin Use and Risk of Subarachnoid Hemorrhage: A Case-Control Study Using Large-Scale Claims Data, Stroke. 56, 2597-2604, 2025.
Morisaki Y, Maeda-Minami A, Sato M, Izumi S, Suzuki M, Funakoshi R, Mano Y. Association Between Frailty and Use of Potentially Inappropriate Medications in Elderly Hospitalized Patients: A Cross-Sectional Study, In Vivo. 39, 2986-2992, 2025.
Morisaki Y, Takashima M, Maeda-Minami A, Izumi S, Suzuki M, Funakoshi R, Mano Y. Relationship Between Frailty and Drug Burden Index in Older Hospitalized Patients, In Vivo. 39, 1649-1792, 2025.
Uozumi H, Kawakami S, Matsui Y, Mori S, Sato A. Passion fruit seed extract protects hydrogen peroxide-induced cell damage in human retinal pigment epithelium ARPE-19 cells. Sci Rep. 15, 1715, 2025.
2024 (79 papers)
Ishii R, Ohigashi T, Maruo K, Gosho M. geessbin: an R package for analyzing small-sample binary data using modified generalized estimating equations with bias-adjusted covariance estimators. BMC Medical Research Methodology. 24, 277, 2024.
Maruo K, Ishii R, Yamaguchi Y, Ohigashi T, Gosho M. Small sample adjustment for inference without assuming orthogonality in a mixed model for repeated measures analysis. Journal of Biopharmaceutical Statistics. 1-15, 2024. doi:10.1080/10543406.2024.2420632. Online ahead of print.
Okubo R, Ohigashi T, Kondo M, Tsunoda R, Kai H, Saito C, Hoshino J, Okada H, Narita I, Maruyama S, Wada T, Yamagada K. Associations of anaemia and iron deficiency with health-related quality of life in patients with chronic kidney disease stage G3b-5 in Japan: sub analysis of the Reach-J CKD cohort study. BMC Nephrology. 25, 414, 2024.
Hoshino J, Ohigashi T, Tsunoda R, Ito Y, Kai H, Saito C, Okada H, Narita I, Wada T, Maruyama S, Pisoni R, Pecoits-Filho R, Yamagata K. Physical activity and renal outcome in diabetic and non-diabetic patients with chronic kidney disease stage G3b to G5. Scientific Reports. 14, 26378, 2024.
Shinya Masadome, Taku Harada, Reward Design Using Large Language Models for Natural Language Explanation of Reinforcement Learning Agent Actions, IEEJ Transactions on Electrical and Electronic Engineering, Vol.20, No.8, pp.1203-1211, 2025
Kuo, Yu-Cheng, Taku Harada, Optimizing Job Shop Scheduling with Deep Q-Network for Robust Performance, Proceedings of 2024 Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems, 2024.
Beran K, Abrahamsson B, Charoo N, Cristofoletti R, Holm R, Kambayashi A, Langguth P, Mehta M, Parr A, Polli J, Shah V, Dressman J. Biowaiver monographs for immediate-release solid oral dosage forms: Lemborexant. J Pharm Sci114(2), 644-659, 2025.
Beran K, Abrahamsson B, Charoo N, Cristofoletti R, Holm R, Kambayashi A, Langguth P, Mehta M, Parr A, Polli J, Shah V, Dressman J. Biowaiver monographs for immediate-release solid oral dosage forms: Voriconazole. J Pharm Sci114(2), 660-680, 2025.
Aoyama Y, Yamazaki H, Nishimura K, Nomura M,Shigehiro T, Suzuki T, Zang W, Tatara Y, Ito H, Hayashi Y, Koike Y, Fukumoto M, Tanaka A, Zhang Y, Saika W, Hasegawa C, Kasai S,Kong Y, Minakuchi Y, Itoh K, Yamamoto M,Toyokuni S, Toyoda A, Ikawa T, Takaori-Kondo A, Inoue D. Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages. Blood. 145:1149-1163, 2025.
Sakai SA, Saeki K, Chi S, Hamaya Y, Du J, Nakamura M, Hojo H, Kojima T, Nakamura Y, Bando H, Kojima M, Suzuki A, Suzuki Y, Akimoto T, Tsuchihara K, Haeno H, Yamashita R, Kageyama SI. Mathematical modeling predicts optimal immune checkpoint inhibitor and radiotherapy combinations and timing of administration. Cancer Immunol Res. 13(3):353-364, 2025.
Sase M, Sato T, Sato H, Miya F, Zhang S, Haeno H, Kajita M, Noguchi T, Mori Y, Ohteki T. Comparative analysis of tongue cancer organoids among patients identifies the heritable nature of minimal residual disease. Dev Cell. 60(3):396-413.e6. 2025.
Watanabe M, Haeno H, Mimaki S, Tsuchihara K. Multistage carcinogenesis in occupational cholangiocarcinoma: the impact of clonal expansion and risk estimation. Genes Environ. 46(1):21. 2024.
Usui, N., Nakata, J., Uehata, A., Kojima, S., Hisadome, H., Inats, A., Tsubaki, A., Saitoh, M., Ando, S., Kitayama, T., Maikusa, K., Nishiyama, Y. and Suzuki, Y. Determinants of longitudinal changes in exercise capacity in patients with independent functioning on hemodialysis,Physical Therapy105, pzae147, 2024.
Ando, S. An index for measuring departure from an anti-sum-symmetry model for square contingency tables with ordered categories, Biometrical Letters61, 101-113, 2024.
Usui, N., Nakata, J., Uehara, A., Kojima, S., Ando, S., Saitoh, M., Inatsu, A., Hisadome, H., Nishiyama, Y. and Suzuki, Y. Association of physiological reserve obtained from cardiopulmonary exercise testing and frailty with all-cause mortality in hemodialysis patients, Clinical Journal of the American Society of Nephrology 20, 420-431, 2025.
Ando, S. and Kikuchi, T. Parsimonious cumulative odds-symmetry model and its decomposition for square tables with ordered categories, Journal of Statistical Theory and Practice19, article number 4, 2025.
Komori, K., Abiko, F., Ichikawa, T., Ando, K., Shigeeda, R., Yamaguchi, T., Kurusu, K., Arai, M., Misawa, K., Ando, S., Koyama, K., Shimizu, K., Nakayama, Y., Mikayama, Y., Suzuki, Y., Rino, Y. and Saito, A. Impact of perioperative rehabilitation on postoperative length of hospital stay for patients with gastric cancer, Anticancer Research45, 817-822, 2025.
Komori, K., Yamada, T., Ando, S., Nagasawa, S., Kanematsu, K., Morita, J., Tanabe, Mie, Nakayama, Y., Rino, Y., Saito, A., Ogata, T. and Oshima, T. Clinical significance of residual lymph node metastasis in predicting recurrence after preoperative chemotherapy and surgery for gastric cancer, Anticancer Research45, 1205-1214, 2025.
Sato T, Yagi A, Seo T, Sphericity Test on Variance-Covariance Matrix with Monotone Missing Data, Journal of Statistical Theory and Practice, 19, article number 16, 2025.
Ryosuke Minami, Narumi Yoneda, Ryo Hatano, Hiroyuki Nishiyama: Classifying MCI with rs-fMRI and deep learning, Proceedings of the Joint Symposium of The Thirtieth International Symposium on Artificial Life and Robotics (AROB 30th 2025), pp. 9-14, 2025.
Yi C, Kitamura Y, Maezawa S, Namekawa SH, Cairns BR. ZBTB16/PLZF regulates self-renewal and differentiation of juvenile spermatogonial stem cells through an extensive transcription factor-chromatin poising network. Nat. Struct. Mol. Biol., 32(7):1227-1240, 2025.
Kitamura Y, Takahashi K, Maezawa S, Munakata Y, Sakashita A, Kaplan N, Namekawa SH. CTCF-mediated 3D chromatin predetermines the gene expression program in the male germline. Nat. Struct. Mol. Biol., 32(7):1213-1226, 2025.
Hayashi Y, Kaneko J, Ito-Matsuoka Y, Takehara A, Funakoshi M, Maezawa S, Shirane K, Furuya S, Matsui Y. Control of epigenomic landscape and development of fetal male germ cells through L-serine metabolism. iScience. 27(9):110702. 2024.
Takikawa M, Nakano A, Krishnaraj J, Tabata Y, Watanabe Y, Okabe A, Sakaguchi Y, Fujiki R, Mochizuki A, Tajima T, Sada A, Matsushita S, Wakabayashi Y, Araki K, Kaneda A, Ishikawa F, Sadaie M, and Ohki R. Extrinsic induction of apoptosis and tumor suppression via the p53-Reprimo-Hippo-YAP/TAZ-p73 pathway, Proc. Natl. Acad. Sci. USA 122, e2413126122, 2025
Sekiya S, Mano Y, Suzuki T, Tanaka R, Harigai S, Shikamura Y. Effect of Dental Follow-Up on Dental Consultation and Checkup Rates for Patients With Diabetes: A Multicenter Before–After Study. Cureus Journal of Medical Science. 16, 12, e75145. 2024.
Maeda-Minami A, Takashima M, Morisaki Y, Ehara S, Kato S, Saito K, Tanaka T, Shikamura Y, Mano . Y. Characteristics of drugs with oral frailty patients among community pharmacy visitors： a cross－sectional study. BMC Oral Health. 24, 1, 1514. 2024.
Aoyama Y, Yamazaki H, Nishimura K, Nomura M, Shigehiro T, Suzuki T, Zang W, Tatara Y, Ito H, Hayashi Y, Koike Y, Fukumoto M, Tanaka A, Zhang Y, Saika W, Hasegawa C, Kasai S, Kong Y, Minakuchi Y, Itoh K, Yamamoto M, Toyokuni S, Toyoda A, Ikawa T, Takaori-Kondo A, Inoue D. Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages. Blood. 145:1149-1163, 2025
Alavattam K. G., Esparza J. M., Hu M., Shimada R, Kohrs A. R., Abe H, Munakata Y, Otsuka K, Yoshimura S, Kitamura Y, Yeh Y. H, Hu Y. C., Kim J, Andreassen P. R., Ishiguro K. I., Namekawa, S. H. ATF7IP2/MCAF2 directs H3K9 methylation and meiotic gene regulation in the male germline, Genes & Development. 38(3-4), 115–130, 2024.
Otsuka K, Sakashita A, Maezawa S, Schultz R.M., Namekawa S.H., KRAB zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution. Genome Res. 35(3):417–31, 2025.
Maeda-Minami A, Yoshino T, Katayama K, Horiba Y, Hikiami H, Shimada Y, Namiki T, Tahara E, Minamizawa K, Muramatsu S, Yamaguchi R, Imoto S, Miyano S, Mima H, Uneda K, Nogami T, Fukunaga K, Watanabe K. Machine Learning Model for Predicting Cold-Heat Pattern in Kampo Medicine: A Multicenter Prospective Observational Study, Front Pharmacol. 15, 1412593, 2024.
Koki Maruyama, Shun Sawada, Hidefumi Ohmura, Kouichi Katsurada, Speech Synthesis from IPA Sequences through EMA Data, In Proc. APSIPA2024, 120, 2024
Honoka Hida, Shun Sawada, Kouichi Katsurada, Takuro Shibayama, Hidefumi Ohmura, Flexible Melody Harmonization with Rhythmic Complexity based on Cognitive Music Theory, In Proc. AIMC2024, 2024.
Hiroto Kuramitsu, Kaiyu Suzuki and Tomofumi Matsuzawa, N-Tuple Network Search in Othello Using Genetic Algorithms, Games, Vol. 16, No. 1:5, pp. 1-11, 2025
Shu Sekiya, Rei Tanaka, Hisashi Iijima, Yoshio Nakano, Satoru Miyazaki, Atsushi Toyomi, Hajime Hashiba, Masanori Nagatsu, Yoshiaki Shikamura, A Nationwide Survey on Medication Follow-up Care by Community Pharmacists: From The Japanese Nationwide Pharmacy Collaboration Survey in 2023, YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Vol.144, pp 805-813, 2024
Satoru Shinoda, Ayumu Uehara, Ryuya Yahagi, Takuya Yoshimoto and Kouji Tahata,35. Satoru Shinoda, Ayumu Uehara, Ryuya Yahagi, Takuya Yoshimoto and Kouji Tahata, Generalized Marginal Cumulative Homogeneity Model for Multi-way Contingency Tables, YJournal of Statistical Theory and Practice, 18, 47, pp 1-14, 2024.
Kengo Fujisawa, Koki Makishima and Kouji Tahata, Asymmetry Plus Association Models for Ordinal Square Contingency Tables, Journal of Statistical Theory and Applications, 23, pp 427–441, 2024.
Satoru Shinoda, Takuya Yoshimoto, and Kouji Tahata,Visualizing departures from marginal homogeneity for square contingency tables with ordered categories, Information Visualization, pp 1-14, 2024.
Hisaya Okahara and Kouji Tahata, A generalized ordinal quasi-symmetry model and its separability for analyzing multi-way tables, Japanese Journal of Statistics and Data Science, pp 1-26, 2025
Hirai K, Ishii T, Aijima A, Yokota N, Miyamoto Y, Higashi K, Iwasaki Y, Ito R, Higashi N, Akiyama H, Development of a method for simultaneous analysis of glycosaminoglycan disaccharides and evaluating the quality of chondroitin sulfate and hyaluronic acid in food raw materials, Food Chem. X, 25, 102239, 2025.
Nozaki Y, Suwa F, Furuya K, Komeno M, Hoshino S, Mizunoe Y, Higashi K, Kobayashi M, Higami Y, The effects of WWP1 overexpression on the golgi apparatus stress response and proteoglycan production in adipocytes, Sci. Rep., 14, 29004, 2024.
Yuxi Yang, Koki Nakayama, Shunpei Okada, Kazuki Sato, Takeshi Wada, Yuriko Sakaguchi, Ayaka Murayama, Tsutomu Suzuki, Masayuki Sakurai, ICLAMP: a novel technique to explore adenosine deamination via inosine chemical labeling and affinity molecular purification, FEBS Lett. Vol.598, pp1080-1093, 2024
A Simple Negative Benchmark Generation for Safety Checking, In International Conference on AI-empowered Software Engineering - AIESE 2024 Formerly Joint Conference on Knowledge-based Software Engineering – JCKBSE, 2024(Peer-reviewed)
Efficient Inductive Logic Programming Based on Neural Networks, Tomo Nakazawa, Moeko Okawara, Tsutomu Kumazawa, Yasushi Kambayashi, Munehiro Takimoto, Eleventh Annual Conference on Computational Science and Computational Intelligence, to appear. (Peer-reviewed)
Multi-grain Parallel Processing of Intuctive Logic Programming, Moeko Okawara, Munehiro Takimoto, Eleventh Annual Conference on Computational Science and Computational Intelligence, to appear. (Peer-reviewed)
Sato K, Miura K, Tamori S, Akimoto K, Identification of a Gene Expression Signature to Predict the Risk of Early Recurrence and the Degree of Immune Cell Infiltration in Triple-negative Breast Cancer. Cancer Genomics Proteomics. 21(3):316-326. 2024.
Matsuoka I, Kasai T, Onaga C, Ozaki A, Motomura H, Maemura Y, Tada Y, Mori H, Hara Y, Xiong Y, Sato K, Tamori S, Sasaki K, Ohno S, Akimoto K, Co‑expression of SLC20A1 and ALDH1A3 is associated with poor prognosis, and SLC20A1 is required for the survival of ALDH1‑positive pancreatic cancer stem cells. Oncol Lett. 28(3):426. 2024.
Nakagawa Y, Sozu T. Improvement of midpoint imputation for estimation of median survival time for interval-censored time-to-event data. Therapeutic Innovation & Regulatory Science, 2024 (Published online).
Ito S, Nakajima Y, Fukuda H, Izumi C, Nakazawa G, Yamashita H, Matsuhisa H, Inoko M, Toyoda S, Takiuchi S, Kataoka T, Izumiya Y, Abe Y, Sozu T, Sakata Y, Emoto M, Inoue T, Kitakaze M. Rationale and design of prospective, multicenter, double-arm clinical trial to investigate the efficacy of tofogliflozin on left ventricular diastolic dysfunction in patients with heart failure with preserved ejection fraction and type 2 diabetes mellitus (TOP-HFPEF Trial). Cardiovascular Drugs and Therapy. 2024(Online ahead of print).
Yuki Ando, Asanao Shimokawa, Detecting differentially expressed genes from RNA-seq data using fuzzy clustering, International Journal of Biostatistics, 20(2), 407-417, 2024.
Yuki Ando, Asanao Shimokawa, An approach based on clustering for detecting differentially expressed genes in microarray data analysis, Communications for Statistical Applications and Methods, 31(5) 571-584, 2024.
Kojima, Y., Fujieda, S., Zhou, L., Takikawa, M., Kuramochi, K., Furuya, T., Mizumoto, A., Kagaya, N., Kawahara, T., Shin-ya, K., Dan, S., Tomida, A., Ishikawa, F., and Sadaie, M. Cytochrome P450 2J2 is required for the natural compound austocystin D to elicit cancer cell toxicity. Cancer Sci. 115, 3054-3066, 2024
Kabasawa M, Furuta M, Ibayashi Y, Kanemaru K, Kohatsu H, Kuramochi F, Yamatoya K, Nakata K, Nakamura Y, Tomoshige S, Ohgane K, Furuyama Y, Takasawa R, Kobayashi S, Sugawara F, Ikekita M, Kuramochi K. Plakevulin a induces apoptosis and suppresses IL-6-induced STAT3 activation in HL60 cells. Bioorg. Med. Chem. Lett. 110: 129886, 2024.
Iguchi H, Katsuzawa T, Saruta C, Sadakata T, Kobayashi S, Sato Y, Sato A, Sano Y, Maezawa S, Shinoda Y, Furuichi T. Calcium-dependent activator protein for secretion 2 is involved in dopamine release in mouse midbrain neurons. Front Mol Neurosci.18;17:1444629, 2024.
Yoneyama Y, Zhang RR, Kimura M, Cai Y, Adam M, Parameswaran S, Masaki H, Mizuno N, Bhadury J, Maezawa S, Ochiai H, Nakauchi H, Potter SS, Weirauch MT, Takebe T. Inter-cellular mRNA Transfer Alters Human Pluripotent Stem Cell State. bioRxiv [Preprint], 2024.06.27.600209, 2024.
Shirahama, H., Tani, Y., Tsukahara, S., Okamoto, Y., Hasebe, A., Noda, T., Ando, S., Ushijima, M., Matsuura. M. and Tomida, A., Induction of stearoyl-CoA desaturase confers cell density-dependent ferroptosis resistance in melanoma, Journal of Cellular Biochemistry, 125(4): e30542, 2024.
Usui, N., Nakata, J., Uehata, A., Kojima, S., Saitoh, S., Chiba, Y., Ando, S., Inatsu, A., Hisadome, H., Ota, S. and Suzuki, Y. Comparison of intradialytic continuous and interval training on hemodynamics and dialysis adequacy: A crossover randomized controlled trial, Nephrology (Carlton), 29(4):214-221, 2024.
Ando, S., Momozaki, T., Masusaki, Y. and Tomizawa, S., An index for measuring degree of departure from symmetry for ordinal square contingency tables, Journal of the Korean Statistical Society 53, 883-905, 2024.
Komori, K., Yamada, T, Ando, S., Hashimoto, I., Watanabe, H., Maezawa, Y., Fujikawa, H., Sawazaki, S., Numata, M., Aoyama, T., Yukawa, N., Rino, Y., Saito, A., Ogata, T. and Oshima,T., Comparison of survival between ypStage and pStage in gastric cancer, Anticancer Research, 44(6), 2661-2670, 2024.
Ando, S., Yamamoto, K. and Tomizawa, S. Cumulative ordinal quasi-symmetry model and its separation for square contingency tables with ordered categories, Biometrical Letters, 61(1), 85-100, 2024.
Ando, S., Fujimoto, K. and Tomizawa, S., A measure of departure from marginal homogeneity using continuation odds for square contingency tables with ordered categories, Sankhya B 86, 311-332, 2024.
Khrennikov A, Iryama S, Basieva I, Sato K. Biosystems, Quantum-like environment adaptive model for creation of phenotype. Biosystems, 242:105261. 2024.
Yoshimoto T, Shinoda S, Yamamoto K, Tahata K. Bayesian Predictive Probability Based on a Bivariate Index Vector for Single-Arm Phase II Study With Binary Efficacy and Safety Endpoints. Pharm Stat. doi: 10.1002/pst.2431. Online ahead of print. 2024 .
Tahata Kouji, and Kohei Matsuda, Diagonals–Parameter Symmetry Model and Its Property for Square Contingency Tables with Ordinal Categories, Symmetry , 16(6 ): 768, 2024. https://doi.org/10.3390/sym16060768
Y. Mizumoto, A. Hirakawa, Y. Sugiura, T. Nishikawa, K. Nishimoto, Y. Mano, T. Higashi, Determination of three C18-oxygenated steroids in adrenal lesion segments in primary aldosteronism by super-selective adrenal venous sampling and LC/ESI-MS/MS, Biomed Chromatogr. 38(5): e5841, 2024.
Yoshida N, Maeda-Minami A, Ishikawa H, Mutoh M, Tomita Y, Kobayashi R, Hashimoto H, Inoue K, Hirose R, Dohi O, Itoh Y, Mano Y, Prevalence of colonoscopy in Japan using a large-scale health claims data compared to esophagogastroduodenoscopy, J Gastroenterol, 59(6):457-467, 2024.
Yuta Okumura, Satoru Goto, Masahiro Ishiguro, Megumi Minamide, Kanji Hasegawa, Yasunari Mano, Tomohiro Tsuchida, Classification of Therapeutic Antibodies based on the Analysis of their Side Effects, Japanese Journal of Drug Informatics, 26 (2), 57-64, 2024.
Kasai S, Ogawa N, Takagi M, Takahashi Y, Makino K, Arita H, Takahashi H, Yoshizawa K. Fentanyl Analogs Exert Antinociceptive Effects via Sodium Channel Blockade in Mice. Biol Pharm Bull. 47: 872-877, 2024.
Shibuya T, Sato A, Nishimoto-Kusunose S, Yoshizawa K, Higashi T. Further evidence for blood-to-brain influx of unconjugated bile acids by passive diffusion: Determination of their brain-to-serum concentration ratios in rats by LC/MS/MS. Steroids. 204: e109397, 2024.
Ryo Okamoto, Koki Toya, Yoko Ogino, ＊ Akira Sato. Down-regulation of long noncoding RNA TP73-AS1 confers resistance to temozolomide in human glioblastoma cells. Nucleosides, Nucleotides & Nucleic Acids,43(1), 86-98, 2024.
Chinatsu Kurasaka, Nana Nishizawa, Yoko Ogino, Akira Sato. Anticancer sensitivity and biological aspect of 5-fluorouracil-resistant human colorectal cancer HCT116 cells in three-dimensional culture under high- and low-glucose conditions. Nucleosides, Nucleotides & Nucleic Acids, 43(8), 870-880, 2024.
Ishii T, Aijima A, Yokota N, Hirai K, Higashi K, Iwasaki Y, Ito R, Higashi N, Akiyama H. Development of an Analytical Method for Unsaturated Disaccharides from Heparan Sulfate Using Dansylhydrazine Derivatization and High-Performance Liquid Chromatography with Fluorescence Detection. Biol. Pharm. Bull., 47, 1054-1057, 2024.
Shi J, Onuki Y, Kawanami F, Miyagawa N, Iwasaki F, Tsuda H, Takahashi K, Oku T, Suzuki M, Higashi K, Adachi H, Nishimura Y, Nakajima M, Irimura T and Higashi N. The uptake of heparanase into mast cells is regulated by its enzymatic activity to degrade heparan sulfate. Int. J. Mol. Sci., 25, 6281, 2024.
Ishii T, Hirai K, Higashi K, Aijima A, Yokota N, Toida T, Iwasaki Y, Ito R, Higashi N, Akiyama H. Novel simultaneous analysis of 18 types of glycosaminoglycan-derived disaccharides using 4-aminobenzoic acid ethyl ester derivatization by HPLC with fluorescence detection. Anal. Bioanal. Chem., in press.
Naseem A. Charoo, N. Selvasudha, Zahira Nala Kath, Bertil Abrahamsson, Rodrigo Cristofoletti, Atsushi Kambayashi, Peter Langguth, Mehul Mehta, Alan Parr, James E. Polli, Vinod P. Shah, Jennifer Dressman. Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Fexofenadine. Journal of Pharmaceutical Sciences, 113(9):2981-2993, 2024.
Yoshinori Takahashi, Atsushi Kambayashi, Physiologically based in vitro – in vivo correlation of modified release oral formulations with non-linear intestinal absorption: a case study using mirabegron. European Journal of Pharmaceutics and Biopharmaceutics 204:114479, 2024.
Atsushi Kambayashi, Masaki Iida, Makoto Ishihara, Yoshinori Takahashi, Bertil Abrahamsson, Naseem A. Charoo, Rodrigo Cristofoletti, Peter Langguth, Mehul Mehta, Alan Parr, James E. Polli, Vinod P. Shah, Jennifer Dressman. Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Raltegravir Potassium. Journal of Pharmaceutical Sciences, 113, pp 3137-3144, 2024
Masaki Koide, Naoyuki Matsumoto and Tomofumi Matsuzawa, Caching Method for Information-Centric Ad Hoc Networks Based on Content Popularity and Node Centrality, Electronics, 13(12:2416):1-14,2024.
Toyonari Iwata, Shigeo Akashi and Tomofumi Matsuzawa, An example of peer-to-peer network surveillance systems preventing man-in-the-middle attack, Proceedings of the 2024 5th International Conference on Computing, Networks and Internet of Things, ACM Digital Library, 650-654,2024.
2023 (81 papers)
Ozaki A, Matsuda A, Maemura Y, Tada Y, Kasai T, Nagashima Y, Onaga C, Hara Y, Kitabatake K, Tsukimoto M, Tamori S, Sasaki K, Ohno S, Akimoto K. Luminal B Breast Cancer Coexpressing p62 and ALDH1A3 Is Less Susceptible to Radiotherapy, Anticancer Res. 4, 37-47, 2024.
Maeda-Minami A, Nishikawa T, Ishikawa H, Mutoh M, Makishima Y, Matsuyama Y, Akimoto K, Mano Y, Uemura H. Angiotensin II Receptor Blockers Cause Changes in Prostate-specific Antigen Levels: A Retrospective Cohort Study, Anticancer Res. 43, 5629-5636, 2023.
Ito S, Takahama H, Asakura M, Abe Y, Ajioka M, AnzaiT, Arikawa T, Hayashi T, Higashino Y, Hiramitsu S, Iwahashi N, Izumi C, Kimura K, Kinugawa K, Kioka H, Lim YJ, Matsuoka K, Matsuoka S, Motoki H, Nakamura S, Nakayama T, Nomura A, Sasaoka T, Takiuchi S, Toyoda S, Ueda T, Watanabe T, Yamada A, Yamamoto M, Sozu T, Kitakaze M. Efficacy of azilsartan on left ventricular diastolic dysfunction compared with candesartan: J-TASTE randomized controlled trial. Scientific Reports; 13(1):12517, 2023.
Ueno Y, Yoshida E, Nojiri S, Kato T, Ohtsu T, Takeshita T, Suzuki S, Yoshida H, Kato K, Itoh M, Notomi T, Usui K, Sozu T, Terao Y, Kawaji H, Kato H. Use of clinical variables for preoperative prediction of lymph node metastasis in endometrial cancer. Japanese Journal of Clinical Oncology, 54(1):38-46, 2024.
Sugimoto K, Miyaoka H, Sozu T, Sekikawa N, Wada R, Watanabe Y, Tamura A, Yamazaki T, Ohta S, Suzuki S. Associations of age-adjusted coefficient of variation of R-R intervals with autonomic and peripheral nerve function in non-elderly persons with diabetes. Journal of Diabetes Investigation , 15(2):186-196, 2024.
Mizumachi H, Watanabe M, Ikezumi M, Kajiwara M, Yasuda M, Mizuno M, Imai N, Sakuma M, Shibata M, Watanabe S, Motoyama J, Basketter D, Eskes C, Hoffmann S, Lehmann DM, Ashikaga T, Sozu T, Takeyoshi M, Suzuki S, Miyazawa M, Kojima H. The inter-laboratory validation study of EpiSensA for predicting skin sensitization potential. Journal of Applied Toxicology. (Online ahead of print).
Izawa J, Matsuzaki K, Raita Y, Uehara G, Nishioka N, Yano H, Sudo K, Katsuren M, Ohigashi T, Sozu T, Kawamura T. Intravenous tranexamic acid in percutaneous kidney biopsy: A randomized controlled trial, Nephron, 147(3-4):144-151.2023.
Keita Sonobe, Asanao Shimokawa, Etsuo Miyaoka, Comparative Study on Estimation Methods of Proportional Hazard Models for Interval-Censored Data, International Journal of Medical Research, 12, 233-239, 2023
Mizumoto, A., Yokoyama, Y., Miyoshi, T., Takikawa, M., Ishikawa, F., and Sadaie, M. DHX36 maintains genomic integrity by unwinding G-quadruplexes. Genes Cells, 28(10):694-708, 2023.
Yu Q, Kobayashi SS, Haeno H, Mathematical analysis identifies the optimal treatment strategy for epidermal growth factor receptor-mutated non-small cell lung cancer, Front Oncol, 13:1137966. 2023.
Inoue M, Nakagawa Y, Azuma M, Akahane H, Chimori R, Mano Y, Takasawa R. The PKM2 inhibitor shikonin enhances piceatannol-induced apoptosis of glyoxalase I-dependent cancer cells. Genes Cells. 29(1): 52-62, 2024.
Xiao M,Kondo S, Nomura M, Kato S, Zang W, Akashi T, Viny A, Fukumoto M, Shigehiro T, Ikawa T, Yamazaki H, Tanaka A, Zhang Y, Nishimura K, Hayashi Y, Koike Y, Aoyama Y, Nishikawa H, Kitamura T, Kanai A, Yokoyama A, Fujiwara T, Noguchi H, Lee SC, Toyoda A, Hinohara K, Abdel-Wahab O and Inoue D. BRD9 determines the cell fate of hematopoietic stem cells by regulating chromatin looping.Nat Commun. 14(1):8372, 2023.
Uehata T, Yamada S, Ori D, Vandenbon A, Giladi A, Jelinski A, Murakawa Y, Watanabe H, Takeuchi K, Toratani K, Mino T, Kiryu H, Standley DM, Tsujimura T, Ikawa T, Kondoh G, Landthaler M, Kawamoto H, Rodewald HR, Amit I, Yamamoto R, Miyazaki M and Takeuchi O.Regulation of lymphoid-myeloid lineage bias through Regnase-1/3-mediated control of Nfkbiz. Blood. 2023020903, 2023
Hu M, Yeh YH, Maezawa S, Nakagawa T, Yoshida S, Namekawa SH. PRC1 directs PRC2-H3K27me3 deposition to shield adult spermatogonial stem cells from differentiation. Nucleic Acids Res. 2024 Mar 21;52(5):2306-2322.
Kitamura Y, Takahashi K, Maezawa S, Munakata Y, Sakashita A, Kaplan N, Namekawa SH. CTCF-mediated 3D chromatin predetermines the gene expression program in the male germline. bioRxiv [Preprint]. :2023.11.30.569508, 2023.
Mika Inadomi, Akira Kuzuhara, Shizu Itaka, Aya Ishigaki, Taku Harada, Tomomichi Suzuki,Analysis of the Relationship among Recruitment Evaluations and Personality Impressions using Video Interviews,Total Quality Science, 9(1):53-61, 2023.
Ryuya Shirata, Taku Harada, A Proposal of a Method to Determine the Appropriate Learning Period in Stock Price Prediction Using Machine Learning, IEEJ Transactions on Electrical and Electronic Engineering, 19(5):726-732, 2024.
Ando, S., Generalized sum-asymmetry model and orthogonality of test statistic for square contingency tables, Austrian Journal of Statistics, 53(2), 99-108, 2024.
Ando, S. Measure of deviancy from marginal mean equality based on cumulative marginal probabilities in square contingency tables, Metrika, open access, 2024.
Nakai, K., Lin, H., Yamano, S., Tanaka, S., Kitamoto, S., Saitoh, H., Sakuma, K., Kurauchi, J., Akter, E., Konno, M., Ishibashi, K., Kamata, R., Ohashi, A., Koseki, J., Takahashi, H., Yokoyama, H., Shiraki, Y., Enomoto, A., Abe, S., Hayakawa, Y., Ushiku, T., Mutoh, M., Fujita, Y. and Kon, S. Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway. Nature Communicaions, 14, 7048, 2023.
Akter, E. and Kon, S. Autophagic perturbation caused by reduced lysosomal activity positively regulates cell competition. Autophagy, 19, 1874-1875. 2023.
Yang Y, Nakayama K, Okada S, Sato K, Wada T, Sakaguchi Y, Murayama A, Suzuki T, Sakurai M. ICLAMP: a novel technique to explore adenosine deamination via inosine chemical labeling and affinity molecular purification.FEBS Lett. 598(9):1080-1093, 2024.
Yoshida N, Maeda-Minami A, Ishikawa H, Mutoh M, Kanno Y, Tomita Y, Kobayashi R, Hashimoto H, Inoue K, Hirose R, Dohi O, Itoh Y, Mano Y., Analysis of the development of gastric cancer after resecting colorectal lesions using large-scale health insurance claims data, J Gastroenterol. 58(11):1105-1113, 2023.
Nishimoto-Kusunose S, Hirakawa A, Tanaka A, Yoshizawa K, Makino K, Takahashi H, Higashi T. Drugs possessing aryloxypropanamine pharmacophore, duloxetine, dapoxetine and propranolol, increase allopregnanolone in rat brain: Possible involvement of allopregnanolone in their central nervous system effects. Steroids. 198:109272, 2023.
Nana Nishizawa, Chinatsu Kurasaka, Yoko Ogino, Akira Sato. Regulation of 5-fluorodeoxyuridine monophosphate-thymidylate synthase ternary complex levels by autophagy confers resistance to 5-fluorouracil. FASEB BioAdvances,5(1), 43-51, 2023.
Kaede Tsuda, Chinatsu Kurasaka, Yoko Ogino, Akira Sato. Genomic and biological aspects of resistance to selective poly(ADP-ribose) glycohydrolase inhibitor PDD00017273 in human colorectal cancer cells. Cancer Reports, 6(2), e1709, 2023.
David Plano, Niklas Rudolph, Christoph Saal, Bertil Abrahamsson, Rodrigo Cristofoletti, Atsushi Kambayashi, Peter Langguth, Mehul Mehta, Alan Parr, James E Polli, Vinod P Shah, Naseem Charoo, Jennifer Dressman. Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Isavuconazonium Sulfate. Journal of Pharmaceutical Sciences , 113(2):386-395, 2024.
Yoshiyuki Shirasaka, Atsushi Kambayashi. Food effects on oral drug absorption: Recent advances in understanding mechanisms and quantitative prediction. Drug Metabolism and Pharmacokinetics, 54:100533-100533, 2024.
Kohei Nakamura, Atsushi Kambayashi, Satomi Onoue. Importance of Considering Fed-State Gastrointestinal Physiology in Predicting the Reabsorption of Enterohepatic Circulation of Drugs. Pharmaceutical Research, 41(4):673-685, 2024.
Hiromu Komazawa and Tomofumi Matsuzawa, Distributed attribute-based encryption with small ciphertext, Advances in the Theory of Nonlinear Analysis and its Application, 7(3):31-44, 2023.
Kazuki Yoshida, Kaiyu Suzuki and Tomofumi Matsuzawa, Distributed Representation for Assembly Code, Computers, 12(11:222):1-17,2023.
Okamoto T, Onaga C, Matsuoka I, Ozaki A, Matsuda C, KasaiT, Xiong Y, Harada Y, Sato T, Nakano Y, Mano Y, Miyazaki S, Ishiguro H, Sato K, Tamori S, Sasaki K, Ohno S, Akimoto K. High SLC20A1 Expression Indicates PoorPrognosis in Prostate Cancer. CancerDiagn Progn. :439-448, 2023. doi: 10.21873/cdp.10237.
Kasai T, Tamori S, Takasaki Y, Matsuoka I, Ozaki A, Matsuda C, Harada Y, Sasaki K, Ohno S, Akimoto K. High expression of PKCλ and ALDH1A3 indicates a poor prognosis, andPKCλ is required for the asymmetric cell division of ALDH1A3-positive cancerstem cells in PDAC. Biochem Biophys Res Commun. 669:85-94, 2023. doi: 10.1016/j.bbrc.2023.05.086.
Ayako Maeda-Minami, Tomoki Nishikawa, Hideki Ishikawa, Michihiro Mutoh, Kazunori Akimoto, Yutaka Matsuyama, Yasunari Mano & Hiroji Uemura, Association of PSA variability with prostate cancer developmentusing large-scale medical information data: a retrospective cohort study, Genes and Environment, 45:25, 2023.
Tai Y, Sakaida Y, Kawasaki R, Kanemaru K, Akimoto K, Brombacher F, Ogawa S, Nakamura Y, Harada Y. Foxp3 and Bcl6 deficiencysynergistically induces spontaneous development of atopic dermatitis-like skindisease, Int Immunol. 3:423-435, 2023 doi: 10.1093/intimm/dxad018.
Yagi, A., Seo, T. and Hanusz, Z.Testing equality of twomean vectors with monotone incomplete data. Communicationsin Statistics – Simulation and Computation, 52:506-522, 2023.
Saeki, Y., Seo, T. and Hyakutake, H., Testing parallelismand confidence intervals of level difference in an intraclass correlation modelwith monotone missing data. Communicationsin Statistics – Theory and Methods, 52: 6147-6160, 2023.
Ferdaos N, Harada A, Masuda E, Kasai S, Horaguchi T, Yoshizawa K, Caffeine-Supplemented Diet Prevents Fatigue-Like Behavior inTumor-Bearing Mice, Nutr Cancer. 75: 1005-1013, 2023.
Onishi S, Shionoya K, Sato K, Mubuchi A, Maruyama S, Nakajima T, Komeno M, Miyata S, Yoshizawa K, Wada T, Linhardt RJ, Toida T, Higashi K, Fucosylated heparan sulfate from the midgut gland of Patinopectenyessoensis, Carbohydr Polym. 313: e120847, 2023.
Natori N, Shibano Y, Hiroki A, Taguchi M, Miyajima A, Yoshizawa K, Kawano Y, Hanawa T, Preparation and Evaluation of Hydrogel FilmContaining Tramadol for Reduction of Peripheral Neuropathic Pain, J Pharm Sci. 112: 132-137, 2023.
Nishimoto-Kusunose S, Hirakawa A, Tanaka A, Yoshizawa K, Makino K, Takahashi H, Higashi T. Drugs possessing aryloxypropanaminepharmacophore, duloxetine, dapoxetine and propranolol, increaseallopregnanolone in rat brain: Possible involvement of allopregnanolone intheir central nervous system effects, Steroids, 198: e109272, 2023.
Matsuura K, Sakamaki K, Honda J, Sozu T. Optimal doseescalation methods using deep reinforcement learning in phase I oncologytrials. Journal of BiopharmaceuticalStatistics 33: 639-652, 2023.
Hashizume K, Tsuchida J, Sozu T. Copula-based model forincorporating single-agent historical data into dual-agent phase I cancertrials. Statistics in Biopharmaceutical Research. 16(1): 71-88. 2024.
Ito S, Takahama H, Asakura M, Abe Y, Ajioka M, AnzaiT, Arikawa T, Hayashi T, Higashino Y, Hiramitsu S, Iwahashi N, Izumi C, Kimura K, Kinugawa K, Kioka H, Lim YJ, Matsuoka K, Matsuoka S, Motoki H, Nakamura S, Nakayama T, Nomura A, Sasaoka T, Takiuchi S, Toyoda S, Ueda T, Watanabe T, Yamada A, Yamamoto M, Sozu T, Kitakaze M. Efficacy of azilsartan on leftventricular diastolic dysfunction compared with candesartan: J-TASTE randomized controlled trial. Scientific Reports. 13: 12517. 2023.
Kouji Tahata, Ryohei Auchi, Shuji Ando and Sadao Tomiza. Separation of the refined estimator of the measure for symmetry in squarecontingency tables. Communications in Statistics- Simulation and Computation, 2023. doi: 10.1080/03610918.2023.2231184.
Kento Tsuchiya, Ryo Hatano and Hiroyuki Nishiyama, Detecting deception using machine learning with facial expressions and pulserate, Artificial Life and Robotics, 28:509-519, 2023.
Takaya Yokoo, Ryo Hatano and Hiroyuki Nishiyama, Estimation of habit‑related information from male voice data using machinelearning‑based methods, Artificial Life andRobotics, 28:520-529, 2023.
Nakajima-Takagi Y, Oshima M, Takano J, Koide S, ItokawaN, Uemura S, Yamashita M, Andoh S, Aoyama K, Isshiki Y, Shinoda D, Saraya A, Arai F, Yamaguchi K, Furukawa Y, Koseki H, Ikawa T, and Iwama A. Polycombrepressive complex 1.1 coodinates homeostatic and emergency myelopoiesis. eLife. 12: e83004, 2023.
Ryo Okamoto, Koki Toya, Yoko Ogino, Akira Sato. Down-regulation of long noncoding RNA TP73-AS1 confers resistance totemozolomide in human glioblastoma cells. Nucleosides, Nucleotides &Nucleic Acids, 43(1), 86-98, 2024.
Akira Sato, Akira Shimotsuma, Tetsuya Miyoshi, YuiTakahashi, Naoki Funayama, Yoko Ogino, Akiko Hiramoto, Yusuke Wataya, Hye-SookKim. Extracellular leakage protein patterns in two types of cancer cell death: necrosis and apoptosis. ACS Omega, 8:25059-25065, 2023.
Chinatsu Kurasaka, Nana Nishizawa, Haruka Uozumi, YokoOgino, Akira Sato. Relationship between anticancer sensitivity and cellularrespiration property in 5-fluorouracil-resistant HCT116 human colorectal cancercells. FEBS OpenBio, 13: 1125-1133, 2023.
Tsuyoshi Kiyota, Yuki Ando, Atsushi Kambayashi, DynamicChanges in Gastrointestinal Fluid Characteristics after Food Ingestion AreImportant for Quantitatively Predicting the In Vivo Performance of Oral SolidDosage Forms in Humans in the Fed State, MolecularPharmaceutics 20: 357-369, 2023.
Atsushi Kambayashi, Yoshiyuki Shirasaka, Food effects ongastrointestinal physiology and drug absorption, Drug Metabolism and Pharmacokinetics 48: 100488-100488, 2023.
Atsushi Kambayashi, Mariska de Meijer, Kim Wegman, Ceesvan Veldhuizen, Bertil Abrahamsson, Rodrigo Cristofoletti, Peter Langguth, Mehul Mehta, Alan Parr, James E. Polli, Vinod P. Shah, Jennifer Dressman. Biowaiver Monograph for Immediate-Release Dosage Forms: LevamisoleHydrochloride. Journal of PharmaceuticalSciences 112 :634-639, 2023.
Naseem A. Charoo, Daud B. Abdallah, Daoud T. Ahmed, Bertil Abrahamsson, Rodrigo Cristofoletti, Peter Langguth, Mehul Mehta, AlanParr, James E. Polli, Vinod P. Shah, Atsushi Kambayashi, Jennifer Dressman. Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Levocetirizine Dihydrochloride. Journal ofPharmaceutical Sciences 112: 893-9032023.
Kohei Yamada, Atsushi Kambayashi, Hideyuki Sato, SatomiOnoue, Control and Prediction of Drug Absorption at Mucosal Tissues. YAKUGAKU ZASSHI 143: 349-3522023.
Keisuke Makino, Ryota Tsukada, Atsushi Kambayashi, KoheiYamada, Hideyuki Sato, Satomi Onoue, Self‐micellizing solid dispersion oftacrolimus: Physicochemical and pharmacokinetic characterization. Biopharmaceutics and Drug Disposition 2023. in press
Atsushi Kambayashi, In Silico Modeling Approaches Coupledwith In Vitro Characterization in Predicting In Vivo Performance of DrugDelivery System Formulations. MolecularPharmaceutics 2023.in press
Maezawa S, Yukawa M, Hasegawa K, Sugiyama R, Iizuka M, HuM, Sakashita A, Vidal M, Koseki H, Barski A, DeFalco T, Namekawa SH. PRC1suppresses a female gene regulatory network to ensure testiculardifferentiation. Cell Death Dis. 14:501. 2023. doi: 10.1038/s41419-023-05996-6.
Sakashita A, Ooga M, Otsuka K, Maezawa S, Takeuchi C, Wakayama S, Wakayama T, Namekawa SH. Polycomb protein SCML2 mediates paternalepigenetic inheritance through sperm chromatin. Nucleic Acids Res. 51:6668-6683. 2023. doi: 10.1093/nar/gkad479.
Mizumoto, A., Yokoyama, Y., Miyoshi, T., Takikawa, M., Ishikawa, F., and Sadaie, M. DHX36 maintains genomic integrity by unwindingG-quadruplexes. Genes to Cells 2023. in press
Abubakar SD, Takaki M, Haeno H. Computational modeling oflocoregional recurrence with spatial structure identifies tissue-specificcarcinogenic profiles. Front Oncol. 13:1116210. 2023. doi: 10.3389/fonc.2023.1116210.
Kobayashi Y, Niida A, Nagayama S, Saeki K, Haeno H, Takahashi KK, Hayashi S, Ozato Y, Saito H, Hasegawa T, Nakamura H, Tobo T, Kitagawa A, Sato K, Shimizu D, Hirata H, Hisamatsu Y, Toshima T, Yonemura Y, Masuda T, Mizuno S, Kawazu M, Kohsaka S, Ueno T, Mano H, Ishihara S, Uemura M, Mori M, Doki Y, Eguchi H, Oshima M, Suzuki Y, Shibata T, Mimori K. Subclonalaccumulation of immune escape mechanisms in microsatellite instability-highcolorectal cancers. Br. J Cancer, 2023. doi: 10.1038/s41416-023-02395-8. Online ahead ofprint. PMID: 37596408. in press
Yuki Ando, Asanao Shimokawa, Etsuo Miyaoka, Comparison ofTwo Group Comparative Methods for Genomic Data, Advancesand Applications in Statistics, 88:139-158, 2023.
Hirokazu Murayama, Kaiyu Suzuki, Tomofumi MatsuzawaEvaluation of Accuracy Degradation Resulting from Concept Drift in a Fake NewsDetection System Using Emotional Expression, Applied Sciences, 13: 6054:1-12, 2023.
Kaiyu Suzuki, Tomofumi Matsuzawa, Rapid Training ofPerceiver in a Low-cost Computing Environment, Proceedings of the 37th Annual Conference of the Japanese Society forArtificial Intelligence, 2023(2U4-IS-2c-05):1-7, 2023.
Komori, K., Kano, K., Ando, S., Watanabe, H., Takahashi, K., Maezawa, Y., Fujikawa, H., Sawazaki, S., Numata, M., Aoyama, T., Yamada, T., Tamagawa, H., Yukawa, N., Rino, Y., Ogata, T. and Oshima, T. Clinicopathological characteristics and prognosis of mucinous gastriccancer, Anticancer Research, 4: 2865-2871, 2023.
Kojima, S., Usui, N., Shigetake, M., Uehata, A., Inatsu, A., Ando, S., Matsuzawa, R., Suzuki, Y., Nakata, J., Tsuchiya, T., Hisadome, H., Mawatari, T. and Tsubaki, A. Intramuscular and abdominal fat measured bycomputed tomography and mortality of hemodialysis patients, Nephrology Dialysis Transplantation, 39(2):286-296, 2024.
Mano Y, Abe K, Takahashi M, Higurashi T, Kawano Y, Miyazaki S, Maeda-Minami A, Optimal Administration of Glycyrrhizin AvoidsPharmacokinetic Interactions With High-dose Methotrexate and Exerts aHepatoprotective Effect, Anticancer Res. 43:1493-1501. 2023.
Yuka Nozaki, Masaki Kobayashi, Hiroki Wakasawa, ShunsukeHoshino, Fumika Suwa, Yuko Ose, Ryoma Tagawa, Yoshikazu Higami, Systemicdepletion of WWP1 improves insulin sensitivity and lowers triglyceride contentin the liver of obese mice, FEBSOpen bio 13:1086-1094, 2023.
Akter, E. and Kon, S. Autophagic perturbation caused byreduced lysosomal activity positively regulates cell competition. Autophagy, 19: 1874-1875, 2023.
Yuina Otani, Yuka Nozaki, Yuhei Mizunoe, MasakiKobayashi, Yoshikazu Higami, Effect of mitochondrial quantity and qualitycontrols in white adipose tissue on healthy lifespan: Essential roles ofGH/IGF-1-independent pathways in caloric restriction-mediated metabolicremodeling, Pathology International, 2023. in press
Nakai, K., Lin, H., Yamano, S., Tanaka, S., Kitamoto, S., Saitoh, H., Sakuma, K., Kurauchi, J., Akter, E., Konno, M., Ishibashi, K., Kamata, R., Ohashi, A., Koseki, J., Takahashi, H., Yokoyama, H., Shiraki, Y., Enomoto, A., Abe, S., Hayakawa, Y., Ushiku, T., Mutoh, M., Fujita, Y. and Kon, S. Wnt activation disturbs cell competition and causes diffuse invasion oftransformed cells through NF-κB-MMP21 pathway. Nature Communicaions, in press.
Maeda-Minami A, Yoshino T, Yumoto T, Sato K, Sagara A, Inaba K, Kominato H, Kimura T, Takishita T, Watanabe G, Nakamura T, Mano Y, Horiba Y, Watanabe K, Kamei J. Development of a novel drug informationprovision system for Kampo medicine using natural language processingtechnology, BMC Medical Informatics andDecision Making, 23:119, 2023.
2022 (71 papers)
Kouji Tahata. Advances in Quasi-Symmetry for Square Contingency Tables. Symmetry, 14:1051, 2022.
Kengo Fujisawa and Kouji Tahata. Quasi Association Models for Square Contingency Tables with Ordinal Categories. Symmetry, 14:805, 2022.
Jin J, Ogawa T, Hojo N, Kryukov K, Shimiz K, Ikawa T, Imanishi T, Okazaki T, and Shiroguchi K. Robotic data acquisition with deep learning enables cell image-based prediction of transcriptomic phenotypes. PNAS. 120: e2210283120, 2023.
Takasawa R, Jona A, Inoue M, Azuma M, Akahane H, Ueno Y, Nakagawa Y, Chimori R, Mano Y, Murata Y, Yasuike S, Kaji T. Triphenylbismuth dichloride inhibits human glyoxalase I and induces cytotoxicity in cultured cancer cell lines. J Toxicol Sci. 47:539-546, 2022.
Kohei Nakamura, Atsushi Kambayashi, Satomi Onoue. Quantitative assessment of disintegration rate is important for predicting the oral absorption of solid dosage forms containing poorly soluble weak base drugs. European Journal of Pharmaceutics and Biopharmaceutics 180:23-32, 2022.
Tsuyoshi Kiyota, Atsushi Kambayashi, Toshihide Takagi, Shinji Yamashita. Importance of Gastric Secretion and the Rapid Gastric Emptying of Ingested Water along the Lesser Curvature ("Magenstraße") in Predicting the In Vivo Performance of Liquid Oral Dosage Forms in the Fed State Using a Modeling and Simulation. Molecular pharmaceutics 19:642-653, 2022.
Atsushi Kambayashi, Mika Murano, Shunji Imai, Kenichi Miyata, Katsuji Sugita, Yoshimine Fujii, Masahiro Kinoshita, Akinori Nomura, Takahiro Kimoto, Yoshikazu Miyazaki, Hiroyuki Sakakibara, Sahoe Kakuda, Takuya Tsujimoto, Yuu Fujita, Mayumi Kano, Hideaki Nakamura, Seiichirou Akaogi, Makoto Honda, Makoto Anraku, Noboru Kamada, Kotoe Ohta, Masashi Uchida, Makoto Kataoka, Hiroshi Kikuchi, Shinji Yamashita, Hiromu Kondo, Interspecies differences in gastrointestinal physiology affecting the in vivo performance of oral pharmaceutical solid dosage forms. Journal of Drug Delivery Science and Technology 67:102923, 2022.
Atsushi Kambayashi, Jennifer B Dressman. Towards Virtual Bioequivalence Studies for Oral Dosage Forms Containing Poorly Water-Soluble Drugs: A Physiologically Based Biopharmaceutics Modeling (PBBM) Approach. Journal of pharmaceutical sciences 111:135-145, 2022.
Hao X, Shiromoto Y, Sakurai M, Towers M, Zhang Q, Wu S, Havas A, Wang L, Berger S, Adams PD, Tian B, Nishikura K, Kossenkov AV, Liu P, Zhang R. ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16INK4a levels. Nat. Cell Biol. 1202-1210, 2022. doi: 10.1038/s41556-022-00959-z.
Ichikawa, Y., Seki, N., Honda, T., Sakugawa, M., Hosokawa, S., Bessho, A., Agemi, Y., Shimokawa, T., Otani, S., Nakahara, Y., Naoki, K., Yomota, M., Hosomi, Y., Takiguchi, Y., Tokito, T., Ando, S. and Okamoto, H. Multicenter, single-arm phase II study of modified carboplatin/nab-paclitaxel in untreated performance status 2 patients with advanced non-small cell lung cancer: TORG1426, Translational Cancer Research, 12: 873-886, 2023.
Xue B, Ishiwata Y, Kawano Y, Takahashi H, Negishi K, Aoyama T, Nagata M, Paliperidone-Induced Acute Hyperglycemia Is Caused by Adrenaline Secretion via the Activation of Hypothalamic AMP-Activated Protein Kinase, Biol Pharm Bull. 45:1669-1677, 2022.
Abe K, Maeda-Minami A, Ishizu T, Iwata S, Kobayashi E, Shimoi T, Kawano Y, Hashimoto H, Yamaguchi M, Furukawa T, Miyazaki S, Mano Y, Risk factors for hepatic toxicity of high-dose methotrexate in patients with osteosarcoma, Anticancer Res. 42:1043-105, 2022.
Kawano Y, Obana M, Nagata M, Mano Y, Katsuyama M, Yamamoto Y, Maeda-Minami A, Negishi K, Takagi M, Shimada S, Aoyama T. The antiplatelet effect of mirtazapine is mediated by co-blocking 5-HT2A and α2-adrenergic receptors on platelets: An in vitro human plasma-based study, Eur J Pharmacol. 917:174640, 2022.
Yamamoto Y, Nakano Y, Murae M, Shimizu Y, Sakai S, Ogawa M, Mizukami T, Inoue T, Onodera T, Takahashi Y, Wakita T, Fukasawa M, Miyazaki S, Noguchi K. Direct Inhibition of SARS-CoV-2 Spike Protein by Peracetic Acid. Int J Mol Sci. 24:20, 2023. doi: 10.3390/ijms24010020.
Akter, E., Tasaki, Y., Mori, Y., Nakai, K., Hachiya, K., Lin, H., Konno, M., Kamasaki, T., Tanabe, K., Umeda, Y., Yamano, S., Fujita, Y. and Kon, S. Non-degradable autophagic vacuoles are indispensable for cell comeptition. Cell Reports 40:11129, 2022.
Igarashi, N., Miyata, K., Loo, T.M., Chiba, M., Hanyu, A., Nihio, M., Kawasaki, H., Zeng, H., Toyokuni, S., Kon, S., Moriyama, K., Fujita, Y. and Takahashi, A. Hepatocyte growth factor derived from senescent cells attenuates cell competition-induced apical elimination of oncogenic cells. Nature Communications 13: s4146, 2022.
Kajiwara, K., Chen, P., Abe, Y., Okuda, S., Kon, S., Adachi, J., Fujita, Y. and Okada, M. Src activation in lipid raft confers epithelial cells with invasive potential to escape from apical extrusion during cell competition. Current Biology 32:3460-3476, 2022.
Mori, Y., Shiratsuchi, N., Sato, N., Chaya, A., Tanimura, N., Ishikawa, S., Kato, M., Kameda, I., Kon, S., Haraoka, Y., Ishitani, T. and Fujita, Y. Extracellular ATP facilitates cell extrusion from epithelial layers mediated by cell competition of apoptosis. Current Biology32: 2144-2159, 2022.
T. Momozaki, Y. Wada, T. Nakagawa and S. Tomizawa, Extension of Gener-alized Proportional Reduction in Variation Measure for Two-Way Contingency Tables. Behaviormetrika, Published Online. 2022.
M. Hyodo, H. Watanabe, S. Nakagawa and T. Nakagawa, Normalizing trans-formation of Dempster type statistic in high-dimensional settings. Communications in Statistics–Theory and Methods, Published Online. 2022.
Y. Saigusa, N. Fukumoto, T. Nakagawa and S. Tomizawa, Measure of departure from conditional partial symmetry for square contingency tables. Journal of Mathematics and Statistics, 18:138–14, 2022.
T. Nakagawa, S. Ohtsuka, An asymptotic expansion for the distribution of Eu-clidean distance-based discriminant function in Normal populations. Journal of Statis-tical Theory and Practice, 16: 6, 2022.
K. Saito, N. Takakubo, A. Ishii, T. Nakagawa and S. Tomizawa, Measures of Departure from Local Marginal Homogeneity for Square Contingency Tables. Symmetry 14: 107, 2022.
Hiroki Watanabe, Masashi Hyodo, Takatoshi Sugiyama and Takashi Seo, Test for equality of standardized generalized variance with different dimensions under high-dimensional settings. Hiroshima Mathematical Journal, 4:185-199, 2022.
Ayaka Yagi, Takashi Seo and Yasunori Fujikoshi, AIC for Growth Curve Model with Monotone Missing Data. American Journal of Mathematical and Management Sciences, 41:185-199, 2022.
Sakashita A, Takeuchi C, Maezawa S, Namekawa SH. Bioinformatics Pipelines for Identification of Super-Enhancers and 3D Chromatin Contacts. Methods Mol Biol. 2577:123-146, 2023.
Tatara M, Ikeda T, Namekawa SH, Maezawa S. ATAC-Seq Analysis of Accessible Chromatin: From Experimental Steps to Data Analysis. Methods Mol Biol. 2577:65-81, 2023.
Hu M, Yeh YH, Munakata Y, Abe H, Sakashita A, Maezawa S, Vidal M, Koseki H, Hunter N, Schultz RM, Namekawa SH. PRC1-mediated epigenetic programming is required to generate the ovarian reserve. Nat Commun. 13:4510, 2022.
Notomi Y, Kazawa T, Maezawa S, Kanzaki R, Haupt SS. Use of Visual Information by Ant Species Occurring in Similar Urban Anthropogenic Environments. Zoological Science 39:529-544, 2022.
Hideki Terai, Kenzo Soejima, Asanao Shimokawa, 他47名, Real-world data analysis of pembrolizumab monotherapy for non-small cell lung cancer utilizing Japanese post-marketing all-case surveillance data, JTO Clinical and Research Reports, 3:100404, 2022.
Nana Nishizawa, Chinatsu Kurasaka, Yoko Ogino, Akira Sato. Regulation of 5-fluorodeoxyuridine monophosphate-thymidylate synthase ternary complex levels by autophagy confers resistance to 5-fluorouracil. FASEB BioAdvances,5: 43-51, 2023.
Kaede Tsuda, Chinatsu Kurasaka, Yoko Ogino, Akira Sato. Genomic and biological aspects of resistance to selective poly(ADP-ribose) glycohydrolase inhibitor PDD00017273 in human colorectal cancer cells. Cancer Reports, 6: e1709, 2022.
A Maeda-Minami, M Hosokawa, Y Ishikura, A Onoda, Y Kawano, K Negishi, S Shimada, T Ihara, M Sugamata, K Tkakeda, Y Mano. Relationship between Leukotriene Receptor Antagonists on Cancer Development in Patients with Bronchial Asthma: a Retrospective Analysis, Anticancer Research, 42:3717-3724, 2022.
Ayako Maeda-Minami, Masayuki Takagi, Yasunari Mano* , Hideki Ishikawa, Yutaka Matsuyama, and Michihiro Mutoh, Association between statins and incidence of cancer in patients with dyslipidemia using large-scale health insurance claims data. Cancer Prevention Research, 16:37–45, 2023. doi:10.1158/1940-6207.CAPR-22-0087.
Masaki Kobayashi, Yuichiro Nezu, Mayu Itoh, Rio Uchida, Tomoya Arikawa, Minami Otsubo, Yuka Nozaki, Ryoma Tagawa, Yuya Fujishima, Norikazu Maeda, Iichiro Shimomura, Yoshikazu Higami, Individual evaluation of aging- and caloric restriction-related changes to distinct multimeric complexes of circulating adiponectin by immunoblotting. Experimental Gerontology,164:111821, 2022. DOI: 10.3390/ijms23031793
Ryoma Tagawa, Masaki Kobayashi, Misako Sakurai, Maho Yoshida, Hiroki Kaneko, Yuhei Mizunoe, Yuka Nozaki, Naoyuki Okita, Yuka Sudo, Yoshikazu Higami, Long-term Dietary Taurine Lowers Plasma Levels of Cholesterol and Bile Acids. International Journal of Molecular Sciences, 23:179, 2022. DOI: 10.3390/ijms23031793.
Takano J, Ito S, Dong Y, Sharif J, Nakajima-Takagi Y, Umeyama T, Han YW, Isono K, Kondo T, Iizuka-Y, MIyai T, Koseki Y, Ikegaya M, Sakihara M, Bardwell VJ, Nakayama M, Ohara O, Hasegawa Y, Hashimoto K, Arner E, Klose RJ, Iwama A, Koseki H, and Ikawa T. PCGF1-PRC links chromatin repression with DNA replication during hematopoietic cell lineage commitment. Nat Commun, 13:7159, 2022.
Nagahata Y, Masuda K, Nishimura Y, Ikawa T, Kawaoka S, Kitawaki T, Nanya Y, Ogawa S, Suga H, Satou Y, Takaori-Kondo A, and Kawamoto H. Tracing the evolutionary history of blood cells to the unicellular ancestor of animals. Blood, 140:2611-2625, 2022.
Ogawa T, Ochiai K, Iwata T, Ikawa T, Tsuzuki T, Shiroguchi K and Takahashi K. Different cell imaging methods did not significantly improve immune cell image classification performance. Plos One, 17:e0262397, 2022.
Kikuchi S, Oe Y, Ito Y, Sozu T, Sasaki Y, Sakata M, Luo Y, Sahker E, Horikoshi M, Seno H, Furukawa TA. Group cognitive behavioral therapy with interoceptive exposure for drug-refractory irritable bowel syndrome: a randomized controlled trial. American Journal of Gastroenterology, 117:668-677. 2022.
Sugimoto K, Miyaoka H, Sozu T, Aihara R, Tsuchida M, Yasuda C. Ishikawa Y. Reference values for nerve conduction and coefficient of variation of R-R interval parameters in healthy subjects with normal ankle reflexes. Peripheral Nerve, 33: 81-98. 2022.
Matsuzaki K, Ohigashi T, Sozu T, Ishida M, Kobayashi D, Suzuki H, Yusuke S, Kawamura T. Identification of high-risk groups in urinalysis: Lessons from the longitudinal analysis of annual check-ups. Healthcare, 10:1074. 2022.
Shimizu D, Taniue K, Matsui Y, Haeno H, Araki H, Miura F, Fukunag M, Shiraishi K, Miyamoto Y, Tsukamoto S, Komine A, Kobayashi Y, Kitagawa A, Yoshikawa Y, Sato K, Saito T, Ito S, Masuda T, Niida A, Suzuki M, & 5 others, Pan-cancer methylome analysis for cancer diagnosis and classification of cancer cell of origin. Cancer Gene Therapy, 29:428-436. 2022.
Naoto Usui, Junichiro Nakata, Akimi Uehata, Shuji Ando, Masakazu Saitoh, Sho Kojima, Akihito Inatsu, Hideki Hisadome and Yusuke Suzuki. Association of cardiac autonomic neuropathy assessed by heart rate response during exercise with intradialytic hypotension and mortality in hemodialysis patients. Kidney International, 101:1054-1062, 2022.
Shuji Ando. Directional measure for analyzing the degree of deviance from generalized marginal mean equality model in square contingency tables. Sankhya B, 8:708-721, 2022.
Shuji Ando. Asymmetry model based on quasi local odds symmetry for square contingency tables. Symmetry, 14:1031, 1-9, 2022.
Masatsugu Okamura, Masaaki Konishi, Yusuke Saigusa, Shuji Ando, Mina Nakayama, Naohiro Komura, Teruyasu Sugano, Kouichi Tamura and Takeshi Nakamura. Impact of grip strength and gait speed on exercise tolerance in patients with pulmonary hypertension without left heart disease. Heart and Vessels, 3:1928-1936, 2022.
Shuji Ando. Relative exponential sum-symmetry model and orthogonal decomposition of the sum-symmetry model for ordinal square contingency tables. Biometrical Letters, 5:1-10, 2022.
Haruna Oyanagi, Naoto Usui, Atsuhiro Tsubaki, Shuji Ando, Masakazu Saithoh, Sho Kojima, Akihito Inatsu, Hideki Hisadome, Shigeyuki Ota and Akimi Uehata. An equation to predict peak heart rate for prescribing exercise intensity in middle-aged to older patients requiring hemodialysis. European Journal of Applied Physiology, 12:2233-2241, 2022.
Shuji Ando. Anti-sum-asymmetry models and orthogonal decomposition of anti-sum-symmetry model for ordinal square contingency tables. Austrian Journal of Statistics, 52:72-86, 2022.
Usami M, Ando K, Shibuya A, Takasawa R, Yokoyama H. Crystal structures of human glyoxalase I and its complex with TLSC702 reveal inhibitor binding mode and substrate preference. FEBS Lett. 596:1458-1467, 2022.
Yoshizawa K, Ukai S, Kuroda J, Yamauchi T, Yamada D, Saitoh A, Iriyama S, Nishino S, Miyazaki S. Alfaxalone improved in acute stress-induced tactile hypersensitivity and anxiety-like behavior in mice. Neuropsychopharmacol Rep. 42:213-217, 2022.
Yamauchi T, Yoshioka T, Yamada D, Hamano T, Ikeda M, Kamei M, Otsuki T, Sato Y, Nii K, Suzuki M, Iriyama S, Yoshizawa K, Nishino S, Ichikawa H, Miyazaki S, Saitoh A. High-frequency ultrasound exposure improves depressive-like behavior in an olfactory bulbectomized rat model of depression. Neuroreport. 33:445-449, 2022.
Yamauchi T, Yoshioka T, Yamada D, Hamano T, Ohashi M, Matsumoto M, Iio K, Ikeda M, Kamei M, Otsuki T, Sato Y, Nii K, Suzuki M, Ichikawa H, Nagase H, Iriyama S, Yoshizawa K, Nishino S, Miyazaki S, Saitoh A. Cold-Restraint Stress-Induced Ultrasonic Vocalization as a Novel Tool to Measure Anxiety in Mice. Biol Pharm Bull. 45:268-275, 2022.
Junji Fukuhara and Munehiro Takimoto, Scalar Replacement Considering Branch Divergence, J. Inf. Process, 30: 164-178, 2022.
Tsutomu Kumazawa, Munehiro Takimoto, Yasushi Kambayashi, A safety checking algorithm with multi-swarm particle swarm optimization, Proc. of GECCO Companion 2022, 786-789, 2022.
Junji Fukuhara and Munehiro Takimoto, Automated kernel fusion for GPU based on code motion, Proc. of LCTES 2022, 151-161, 2022.
Yuyun, X, Motomura, H., Tamori, S., Ozaki, A., Onaga, C, Hara, Y., Sato, K., Tahata, K., Harada, Y., Sasaki, K., Yunwen, Z., Ohno, S., Akimoto, K. High expression of CD58 and ALDH1A3 predicts a poor prognosis in basal-like breast cancer, Anticancer Res., 42:5223-5232, 2022.
Ozaki, A., Motomura, H., Tamori, S., Onaga, C., Nagashima, Y., Kotori, M., Matsuda, C., Matsuda, A., Mochizuki, N., Sato, T., Hara, Y., Sato, K., Miyagi, Y., Nagashima, Y., Hanawa, T., Harada, Y., Yuyun, X., Sasaki, K., Ohno, S., Akimoto, K. High Expression of p62 and ALDH1A3 Is Associated With Poor Prognosis in Luminal B Breast Cancer, Anticancer Res., 42:3299-3312, 2022.
Onaga, C., Tamori, S., Matsuoka, I., Ozaki, A., Motomura, H. Nagashima, Y., Sato, T., Sato, K., Tahata, K., Yuyun, X., Nakano, Y., Mano, Y., Miyazaki, S., Sasaki, K., Ohno, S., Akimoto, K. High SLC20A1 Expression Is Associated With Poor Prognosis for Radiotherapy of Estrogen Receptor-positive Breast Cancer, Cancer Diagnosis&Prognosis., 2:429-442, 2022.
Onaga, C., Tamori, S., Matsuoka, I., Ozaki, A., Motomura, H. Nagashima, Y., Sato, T., Sato, K., Yuyun, X., Sasaki, K., Ohno, S., Akimoto, K. High expression of SLC20A1 is less effective for endocrine therapy and predicts late recurrence in ER-positive breast cancer, PLoS One, 17:e0268799, 2022.
Tomofumi Matsuzawa, Akiyoshi Ishii, Evaluation of PSO Algorithm Considering Obstacle Avoidance in Evacuation Guidance. Advances in the Theory of Nonlinear Analysis and its Application, 6:318-335, 2022.
Tomofumi Matsuzawa, Kyosuke Ichikawa, Implementation and Evaluation of HTTP/3 Connectivity Check Using Happy Eyeballs Algorithm. Network, 2:389-397, 2022.
Tomofumi Matsuzawa, Akito Fukai, Proposal and Evaluation of a Dynamic Path Finding Method Using Potential Values Considering Time Series in Automatic Driving. Advances in the Theory of Nonlinear Analysis and its Application, 6:460-475, 2022.
Kaiyu Suzuki, Tomofumi Matsuzawa, Model Soups for Various Training and Validation Data. AI, 3:796-808, 2022.