東京理科大学 生命医科学研究所 岩野研究室
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03 / PUBLICATIONS & PRESENTATIONS

Publications

SELECTED OUTPUTS

Preprints

PREPRINT

OxyBLI: A Genetics-Based Approach for In Vivo Real-Time Visualization of Tissue Oxygenation Dynamics

Iwano S, Kato J, Toramaru T, et al.

bioRxiv (2026)

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PREPRINT

A bright synthetic near-infrared luciferin enhances the capabilities of deep-tissue bioluminescence imaging using firefly luciferases

Saito-Moriya R#, Iwano S#, Kitada N, et al.

bioRxiv (2025)

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Published Papers

Researchmapから論文を読み込んでいます。

ARTICLE

Real-time bioluminescence imaging of mycobacteria with Akaluc: a novel method for monitoring drug efficacy

Islam MS, Takeishi A, Tateishi Y, et al.

Scientific Reports 16, 15193 (2026)

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ARTICLE

Assessing leaky expression of Cre-dependent DNA constructs in the mouse genome using sensitive bioluminescent reporters

Nakashiba T, Sugiyama T, Iwano S, Iwama M, Yoshiki A, Miyawaki A, Abe K

Cell Reports Methods 6(4), 101369 (2026)

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ARTICLE

Progenitor effect in the spleen drives early recovery via universal hematopoietic cell inflation

Yogo T, Becker HJ, Kimura T, Iwano S, et al.

Cell Reports 44(2), 115241 (2025)

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ARTICLE

Combined Therapy Targeting MET and Pro-HGF Activation Shows Significant Therapeutic Effect Against Liver Metastasis of CRPC

Kimura S, Iwano S, Akioka T, et al.

International Journal of Molecular Sciences 26(5), 2308 (2025)

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ARTICLE

Lonidamine, a Novel Modulator for the BvgAS System of Bordetella Species

Ota N, Nishida T, Standley DM, Sherif AA, Iwano S, et al.

Microbiology and Immunology 69(3), 133–147 (2025)

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ARTICLE

Akaluc bioluminescence offers superior sensitivity to track in vivo dynamics of SARS-CoV-2 infection

Tamura T, Ito H, Torii S, et al., Iwano S*, et al.

iScience 27(5), 109647 (2024)

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ARTICLE

Secretory GFP reconstitution labeling of neighboring cells interrogates cell–cell interactions in metastatic niches

Minegishi M, Kuchimaru T, Nishikawa K, et al., Iwano S, et al.

Nature Communications 14, 8031 (2023)

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ARTICLE

Development of two mouse strains conditionally expressing bright luciferases with distinct emission spectra as new tools for in vivo imaging

Nakashiba T, Ogoh K, Iwano S, Sugiyama T, et al.

Lab Animal 52(10), 247–257 (2023)

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ARTICLE

Single-cell bioluminescence imaging of deep tissue in freely moving animals

Iwano S, Sugiyama M, Hama H, et al.

Science 359, 935–939 (2018)

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ARTICLE

Quantum yield improvement of red-light-emitting firefly luciferin analogues for in vivo bioluminescence imaging

Kiyama M, Iwano S, Otsuka S, et al.

Tetrahedron 74, 652–660 (2018)

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ARTICLE

A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging

Kuchimaru T#, Iwano S#, Kiyama M, et al.

Nature Communications 7, 11856 (2016)

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ARTICLE

Development of simple firefly luciferin analogs emitting blue, green, red, and near-infrared biological window light

Iwano S, Obata R, Miura C, et al.

Tetrahedron 69, 3847–3856 (2013)

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PATENTS

新規セレンテラジン誘導体

特許第7036343号（JP7036343B2）

木山 正啓、牧 昌次郎、平野 誉、岩野 智、宮脇 敦史

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改変型ルシフェラーゼ

特願2016-165053／PCT/JP2017/030491（WO2018038248A1）

宮脇 敦史、岩野 智

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Modified luciferase

US Patent 10,815,462（US10815462B2）

Atsushi Miyawaki, Satoshi Iwano

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PRESENTATIONS

Researchmapから学会発表を読み込んでいます。

INVITED

INVITED LECTURE

23rd International Symposium on Bioluminescence and Chemiluminescence & 21st International Symposium on Luminescence Spectroscopy

Rayong, Thailand

GENERAL

POSTER / CO-AUTHOR

High-Sensitivity In Vivo Bioluminescence Imaging Enabled by the Near-Infrared Substrate AkaSuke

第48回日本分子生物学会年会

GENERAL

SEMINAR

生物発光を利用したバイオイメージング技術の開発

次世代薬理学セミナー 2025 in 宮崎

GENERAL

POSTER / CO-AUTHOR

生物発光共鳴エネルギー移動を利用した赤色生物発光の高効率化

第15回CSJ化学フェスタ2025

INVITED

INVITED LECTURE

生命科学研究を志向してホタル生物発光反応を進化させる

生物発光化学発光研究会 第35回学術集会

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