Achievements

2026

  1. Nishikawa, M. Drug discovery using ESC-GalNAc. In: Glycoscience: A Global Roadmap 2025 from Japan. Springer (2026).
  2. Kodaki, S., Kondo, M., Minato, J., Itakura, S., Takamura, H., Nishikawa, M., Kadota, I., Kusamori, K., Tanaka, K. Visible-light-induced photocatalytic intermolecular cyclization for synthesis of 2,2-diarylchromanes. Tetrahedron Lett., 179:156034 (2026).
  3. Endo, Y., Kanai, M., Kobayashi, M., Higami, Y., Itakura, S., Nishikawa, M., Kusamori, K. Structural and functional diversity of mitochondria isolated from different cell types. Biol. Pharm. Bull., 49(3):457–466 (2026).
  4. Nishikawa, M., Kusamori, K., Itakura, S. 核酸アジュバントと抗原を対象としたDDSを基盤とする次世代ワクチン開発. クリーンテクノロジー, 36:7–13 (2026).
  5. Lan, M., Meng, F., Gao, L., Giri, A. K., Nishikawa, M., Kusamori, K., Lee, J., Asim, M. H., Arshad, S., Gu, H., Li, Q., Yang, L., Chen, Z., Yang, Z., Qin, J., Cai, Y. Preparation of baicalin nano prodrug and its effect on inhibiting metastasis of triple-negative breast cancer. Biomater. Adv., 178:214464 (2026).
  6. Kanai, R., Seki, T., Yukimura, T., Komatsu, S., Itakura, S., Arce, F. Jr., See, G. L., Kiba, Y., Kitamura, M., Kodama, N., Inoue, Y., Oshizaka, T., Todo, H. Potential enhancement of topical drug delivery using grapefruit-derived nanoparticles modified using TAT peptide. Pharm. Res., 43:495–507 (2026).
  7. Tanifuji, T., Kusamori, K., Tanaka, C., Sakai, H., Itakura, S., Nishikawa, M. Improved messenger RNA stability and biocompatibility through self-gelatinizable nucleic acids. Biotechnol. Bioeng., 123(4):1077–1086 (2026).
  8. Nagashima, Y., Ogino, M., Okiyama, R., Chiwaki, R., Ishii, H., Nohata, K., Nakahara, A., Ozaki, A., Kasai, T., Tamori, S., Ohno, S., Sasaki, K., Akimoto, K. Co-expression of PKCζ and ALDH1A3 is associated with poor chemotherapeutic responses in basal-like breast cancer. Cancer Genomics Proteomics, 23:322–341 (2026).
  9. Suzuki, M., Komeno, M., Yasumura, R., Miwa, A., Enomoto, M., Kotani, H., Matsumoto, K., Akimoto, K., Takahashi, C., Igarashi, K., Higashi, K. Identification of inhibitors for eIF5A2-dependent translation elongation by monitoring the translational efficiency of polyproline motif in mitochondrial fission regulator 1. Biol. Pharm. Bull., 49(2):355–363 (2026).
  10. Inutake, R., Hasegawa, H., Tsurusaki, T., Sakamoto, T., Sato, K., Wada, T. Stereocontrolled synthesis of dimethylamino phosphorochloridate monomers toward stereopure phosphorodiamidate morpholino oligonucleotides. J. Org. Chem., 91:4170–4190 (2026).
  11. Okada, T., Kawada, M., Yoshida, S. Divergent synthesis of 1-aminonaphthalene derivatives via the Diels–Alder reaction of 3-aminoarynes. J. Org. Chem., 91:3744 (2026).
  12. Okada, T., Yoshida, S. Lewis-acid-mediated regioselectivity switching by aromatization-driven rearrangement of 5-amino-1,4-epoxy-1,4-dihydronaphthalenes. Bull. Chem. Soc. Jpn., 99:uoag039 (2026).
  13. Mitsuya, K., Tsurumoto, S., Kurosawa, Y., Koga, R., Hanawa, T., Goto, S. Amyloid fibril formation of human recombinant insulin due to the interfacial hydrophobicity of fluorocarbon polymer membranes. Explor. BioMat-X (2026).
  14. Koga, R., Kinoshita, T., Ishiguro, M., Fujita, M., Chatani, H., Kataoka, H., Yokoyama, H., Hanawa, T., Shitanda, I., Goto, S. Hydrophobic hydration of analgesics and diltiazem complexes explored by electrochemical impedance spectroscopy and diffusion-ordered spectroscopy. Phys. Chem. Chem. Phys., 28(2):1159–1179 (2026).
  15. Endo, A., Mikawa, T., Taiki, T., Nakane, Y., Asakawa, D., Kido, S., Fujimori, K., Takatori, M., Natsume, Y., Matsumoto, K., Hanawa, T. An interdisciplinary infectious disease support team with longitudinal process interventions is associated with lower 28-day mortality in bacteremia: a single-center cohort study. Infect. Control Hosp. Epidemiol., 1–10 (2026).
  16. Kawano, Y., Nomura, K., Natori, N., Oba, T., Ozawa, C., Hirose, K., Hanawa, T. New method for adsorbing pharmaceuticals on mesoporous silica: adsorption behavior of ibuprofen via the sealed and heating method. J. Pharm. Sci., 115:104140 (2026).
  17. Yang, Y., Sakurai, M. Advances in detection methods for A-to-I RNA editing. Methods Mol. Biol., in press (2026).
  18. Yang, Y., Kubota, M., Hasegawa, K., Zeng, C., Nishikura, K., Hamada, M., Sakurai, M. Mitotic phosphorylation of ADAR1 regulates its centromeric localization and is required for faithful mitotic progression. iScience, in press (2026).
  19. Inoue, Y., Onishi, M., Tomita, J., Kodama, N., Suzuki, K., Itakura, S., Nishikawa, M., Yukutake, S., Ishida, Y., Nakata, D., Terao, K. Comprehensive physicochemical and functional characterization of mechanochemically prepared α-mangostin/cyclodextrin inclusion complexes. Next Mater., in press (2026).
  20. Okada, R., Takeuchi, I., Itakura, S., Kusamori, K., Nishikawa, M., Saitoh, A. Development of a temperature-responsive gel formulation containing GGsTop® for treating stomatitis. Polym. J., in press (2026).
  21. Nishikawa, M., Takahashi, Y. 細胞外小胞を基盤とする疾患治療システム開発の現状と課題. Yakugaku Zasshi, in press (2026).
  22. Nishikawa, M., Kusamori, K., Itakura, S. 植物由来細胞外小胞を基盤とする疾患治療システムの開発. Yakugaku Zasshi, in press (2026).

2025

  1. Tanabe, Y., Kamachi, F., Ito, J., Harada, N., Harada, S., Makino, F., Abe, Y., Nakano, N., Izawa, K., Niyonsaba, F., Nishiyama, C., Kitaura, J., Okumura, K., Takahashi, K., Akiba, H., Miyake, S. TIM-4 regulates allergic airway inflammation and mast cell activation by binding to CD300b. J. Asthma Allergy, 2025:1477–1492 (2025).
  2. Ishii, K., Nagata, K., Yamashita, N., Yamazaki, Y., Akimoto, Y., Zhao, W., Inoue, M., Ito, N., Kasakura, K., Nishiyama, C. PU.1 and TGF-β signaling activate the cell-surface expression of CD103 in mast cells and dendritic cells: opposite roles of GATA2 in the expression of mucosal mast cell genes. FEBS J., 292:6117–6133 (2025).
  3. Nagata, K., Kasakura, K., Ishii, K., Ito, N., Hara, M., Nakano, N., Okumura, K., Nishiyama, C. The role of GATA2 in the expression of the soluble decoy receptor ST2/IL1RL1 in human and mouse mast cell. Allergol. Int., 74:637–640 (2025).
  4. Taninaga, Y., Orimoto, G., Miyamoto, M., Yamada, K., Yokoo, H., Demizu, Y., Yoshida, S. Rapid synthesis of proteolysis-targeting chimeras by consecutive click assembly. Bull. Chem. Soc. Jpn., 98:uoaf115 (2025).
  5. Otani, Y., Kawarai, M., Kobayashi, M., Nozaki, Y., Uchida, R., Tezuka, K., Yokoyama, M., Mizunoe, Y., Narita, T., Haeno, H., Miyano, K., Uezono, Y., Higami, Y. Identification of a novel MIPEP splice variant with altered substrate-binding properties. BB Rep., 44:102329 (2025).
  6. Hachiya, K., Mizunoe, Y., Yang, J. J., Uchida, Y., Fukai, H., Esashi, T., Nozaki, Y., Mizuno, S., Takahashi, S., Kobayashi, M., Higami, Y. PARIS/ZNF746 DNA-binding domain deficiency promotes adipose tissue hyperplasia and hepatic lipid accumulation. Sci. Rep., 15:36095 (2025).
  7. Ichihashi, E., Kubota, M., Shiromoto, Y., Sakurai, M. ADAR1 RNA editing enzyme regulates telomeric R-loop formation. Methods Mol. Biol., 2949:109 (2025).
  8. Yang, Y., Sakurai, M. Advances in detection methods for A-to-I RNA editing. WIREs RNA, 16:e70014 (2025).
  9. Kanai, M., Goto, M., Itakura, S., Nishikawa, M., Kusamori, K. Uptake mechanisms and functions of isolated mitochondria in mesenchymal stromal cells. Sci. Rep., 15:44799 (2025).
  10. Nishikawa, M. 薬物動態特性に立脚したNSAIDs選択の最適化. 調剤と情報, 31(15):67–75 (2025).
  11. Obana, S., Itakura, S., Murahashi, M., Nishikawa, M., Kusamori, K. Reconstruction of the lymphatic system by transplantation of a centrifuge-based bioengineered lymphatic tissue. Nat. Commun., 16:10154 (2025).
  12. Maemura, Y., Ozaki, A., Chiwaki, R., Enomoto, M., Tada, Y., Nagashima, Y., Ishii, H., Nohata, K., Kasai, T., Okiyama, R., Harada, Y., Tamori, S., Ohno, S., Sasaki, K., Akimoto, K. High p62 and ALDH1A3 reduce the effectiveness of endocrine therapy in luminal B breast cancer. Cancer Diagn. Progn., 5:677–697 (2025).
  13. Nohata, K., Enomoto, M., Ishiyama, A., Nagashima, Y., Okiyama, R., Kasai, T., Tamori, S., Harada, Y., Ohno, S., Sasaki, K., Akimoto, K. PKCζ, CTNNBIP1 and ALDH1A3 expression in luminal B breast cancer indicates decreased hormone therapy effectiveness. Cancer Diagn. Progn., 5:706–719 (2025).
  14. Hashimoto, M., Itakura, S., Kusamori, K., Yajima, K., Mitsuhashi, S., Hayashi, S., Todo, H., Nishikawa, M. Therapeutic potential of rose hip-derived nanoparticles for psoriatic skin inflammation. ACS Biomater. Sci. Eng., 11:5938–5951 (2025).
  15. Yang, L., Yan, J., Giri, A. K., Lee, J., Kusamori, K., Nishikawa, M., Itakura, S., Gu, H., Li, Q., Chen, Z., Yang, Z., Li, D., Cai, Y. Construction of pH-responsive albumin nanoparticles loaded with baicalin and evaluation of their anti-breast cancer activity. Int. J. Biol. Macromol., 322:146937 (2025).
  16. Matsumoto, S., Itakura, S., Minato, J., Hashimoto, M., Obana, S., Kanai, M., Kobayashi, M., Nishikawa, M., Kusamori, K. Cell observation and analysis with a three-dimensional optical wave field microscope. Biosensors, 15:515 (2025).
  17. Li, Q., Meng, F., Yang, L., García, A. M. D., Parkhats, M., Lee, J., Kusamori, K., Nishikawa, M., Gu, H., Li, Q., Williams, G. R., Yang, Z., Cai, Y. Metabolic reprogramming of tumors: induced immunosuppression and therapeutic prospects of nanoscale drug delivery systems. Mol. Pharm., 22:5193–5211 (2025).
  18. Takahashi, Y., Sato, K., Wada, T. Preparation of boranophosphate DNA via the boranophosphotriester method and synthesis of P-modified DNAs from boranophosphate DNA via an acyl phosphite intermediate. Current Protocols in press.
  19. Ikeda, Y., Yamashita, N., Ito, N., Minamikawa, N., Okamura, H., Yashiro, T., Hachisu, M., Aida, M., Yamada, R., Nagata, K., Nishiyama, C. Immunostimulatory effects of Hyndrickxia coaglans SANK70258. Biosci. Biotechnol. Biochem. 89: 622-632 (2025).
  20. Oishi, K., Nakano, N., Ota, M., Inage, E., Izawa, K., Kaitani, A., Ando, T., Hara, M., Ohtsuka, Y., Nishiyama, C., Ogawa, H., Kitaura, J., Okumura, K., Shimizu, T. MHC class II-expressing mucosal mast cells promote intestinal mast cell hyperplasia in a mouse model of food allergy. Allergy 80: 2297-2309 (2025).
  21. Takahashi, M., Nagata, K., Watanuki, Y., Yamaguchi, M., Ishii, K., Harada, T., Minamikawa, N., Katagiri, M., Zhao, W., Ito, N., Yashiro, T., Nishiyama, C. Kaempferol exerts anti-inflammatory effects by accelerating Treg development via Aryl hydrocarbon receptor-mediated and PU.1/IRF4-dependent transactivation of the Aldh1a2/Raldh2 gene in dendritic cells. Allergy 80:896-900 (2025).
  22. Tojima, R., Nagata, K., Ito, N., Ishii, K., Arai, T., Ito, T., Kasakura, K., Nishiyama, C. Roles of C/EBPa, GATA2, TGF-b signaling, and epigenetic regulation in the expression of basophil-specific protease genes. FEBS Lett. 599:777-786 (2025).
  23. Hamada, M., Yoshida, S. Conditional fluorescent changes of azaylides with fluorescent chromophores, Chem. Lett. 54: upaf033 (2025)
  24. Hoshi, Y., Tabata, S., Yoshida, S. Synthesis of α-arylacetophenone derivatives by Grignard reactions and transformations of arynes via C–C bond cleavage. Chem. Commun. 61: 3752 (2025).
  25. Kawada, M., Tabata, S., Hoshi, Y., Yoshida, S. Thioxanthone Synthesis from Thioureas through Double Aryne Insertion into a Carbon=Sulfur Double Bond. Org. Lett. 27: 827 (2025).
  26. Tanaka, T., Tabata, S., Nakamura, K., Hazama, Y., Sakata, Y., Hosoya, T., Yoshida, S. Synthesis of Multisubstituted Naphthalenes through Consecutive Aryne Reactions. Bull. Chem. Soc. Jpn. 98: uoaf001 (2025).
  27. Yasuda, T., Orimoto, G., Yoshida, S. Three-step click assembly using trivalent platforms bearing azido, ethynyl, and fluorosulfonyl groups. Chem. Commun. 61: 2333 (2025).
  28. Hirose, K., Nitto, R., Yokota, S., Kawano, Y., Yamatoya, K., Tabuchi, A., Suzuki, Y., Hanawa, T. Preparing and Characterizing of Xyloglucan Films Containing Tea Extract for Oral Mucositis. ACS Omega 10, 390–399 (2025).
  29. Yoshioka, Y., Yamamoto, S., Kusamori, K., Nakayama, M., Fujita, H., Goto. A., Iwasaki, S., Nagata, T., Itakura, S., Kusuhara, H., Yokota, T., Hirabayashi, H., Nishikawa, M. Pharmacokinetics and protein binding of cholesterol-conjugated heteroduplex oligonucleotide. J. Control. Release 380: 787-799 (2025).
  30. Jin, J., Kusamori, K., Tanifuji, T., Yamagata, Y., Itakura, S., Nishikawa, M. Biocompatible DNA hydrogel composed of minimized Takumi-shaped DNA nanostructure exhibits sustained retention after in vivo administration. J. Control. Release 377: 704-715 (2025).　東京理科大学プレスリリース https://www.tus.ac.jp/today/archive/20250213_0214.html
  31. Kakuta, K., Sakamoto, T., Sato, H., Sato, K., Wada, T. Stereocontrolled Synthesis and NMR Analysis of PB/PO Chimeric Oligonucleotides. R. Soc. Open Sci. in press (2025).
  32. Akita, T. Curative Treatment for COPD Based on Differentiation Induction by Synthetic Retinoid Am80 and Development of Inhalation Powder. YAKUGAKU ZASSHI 145: 1-6 (2025).
  33. Nozaki, Y., Mizunoe, Y., Kobayashi, M., Higami, Y. WW Domain-Containing E3 UbiquitinProtein Ligase 1 (WWP1) as a Factor in Obesity-Related Metabolic Disorders:Emerging Molecular Mechanisms in Metabolic Tissues. Int. J. Mol.Sci., 26(18): 9172 (2025).
  34. Ishimatsu, M., Taki, K., Hayami, A., Kato, K., Nozaki, Y., Mizunoe, Y., Narita, T., Mori, R., Higami, Y., Kobayashi, M. Co-overexpressionof the caloric restriction-induced mitochondrial factors PGC-1α and MIPEPupregulates Phospho1 expression in adipocytes. FEBS Open Bio,15(10): 1643–1657 (2025).
  35. Mizunoe, Y., Kumagai,M., Fukai, H., Hachiya, K., Otani, Y., Nozaki, Y., Tezuka, K.,Kobayashi, M., Haeno, H., Saeki, K., Murayama, Y.,Shimano, H., Higami, Y. Caloricrestriction alters NCOA2 splicing to regulate lipid metabolism in subcutaneouswhite adipose tissue. Biochem. Biophys. Res. Commun., 765: 151871 (2025).
  36. Nozaki, Y., Ose, Y., Ohmori, C., Mizunoe, Y.,Kobayashi, M., Saitoh, A., Higami,Y. Depletion of WWP1 Increases Adrb3 Expression and Lipolysis in WhiteAdipose Tissue of Obese Mice. Int. J. Mol. Sci., 26(9):4219 (2025).
  37. Nozaki, Y., Kobayashi,M., Fukuoh, T., Ishimatsu,M., Narita, T., Taki, K., Hirao, Y., Ayabe, S.,Yokoyama, M., Otani, Y., Mizunoe, Y.,Matsumoto, M., Ohno, N., Kaifu, T., Okazaki, S., Goitsuka,R., Nakagawa, Y., Shimano, H., Iwakura, Y., Higami,Y. Mipep deficiency in adipocytes impairsmitochondrial protein maturation and leads to systemic inflammation andmetabolic dysfunctions. Sci. Rep., 15(1): 12839 (2025).
  38. Saito, J.,Yamatani, A., Kojima, Y., Nakakuni, M., Nakano, K., Hirose, K., Nakamura, H., Hanawa,T., and Akabane, M. Stability and Dissolution Behavior Changes After DrugCompounding for Pediatric Cardiovascular Pharmacotherapy. Pharmaceutics,17:535-550(2025).
  39. Okutsu, H., Takahashi, Y., Shiraishi, T., Kashio, U., Sato, K., Wada, T. Synthesis ofP-Modified Chimeric Oligonucleotides via ChemoselectiveCondensation of Nucleoside 3′-H-Phosphonothioate.J. Org. Chem. ;90: 12346–12358 (2025).
  40. Takahashi, Y., Kato, I., Sato, K. Wada,T. Solution-Phase Synthesis of Boranophosphateand Boranophosphate/Phosphorothioate/PhosphateChimeric Oligonucleotides via the H-BoranophosphonateMethod. J. Org. Chem. ;90: 8966-8985 (2025).
  41. Nakamura, N., Kakuta,K., Sato, K., Wada, T. Stereoselective Synthesis of NucleotideAnalog Prodrugs (Protides) via an OxazaphospholidineMethod. J. Org. Chem. ;90: 6434-6442 (2025).
  42. Prevention ofSerious Adverse Drug Reactions and Economic Effects Through Community Pharmacists’ Inquiries, Home Care, and MedicationFollow-up: From The Japanese NationwidePharmacy Collaboration Survey in 2023”, Shu Sekiya, ReiTanaka, Hisashi Iijima,Yoshio Nakano, Satoru Miyazaki, Atsushi Toyomi, Hajime Hashiba, Masanori Nagatsu, Yoshiaki Shikamura, Yakugaku Zasshi,145:707-722, (2025).
  43. Pain-stimulated ultrasoundvocalizations and their impact on painresponse in mice”, SatokaKasai, Saki Ukai, Junpei Kuroda, Tsugumi Yamauchi, Daisuke Yamada, Akiyoshi Saitoh, Satoshi Iriyama, MasashiSuzuki, Kazuki Arita, Yoshio Nakano,Satoru Miyazaki, Kazumi Yoshizawa,PLoS One,20: e0324730, (2025).
  44. Polyamines stimulatethe protein synthesis of theinitiation factor eIF5A2 participatingin mRNA decoding distinct from eIF5A1”, Suzuki M, Suzuki T, NakanoY, Matsumoto K, Manaka H, KomenoM, Tamori S, Sato A, Dohmae N, Akimoto K, Miyazaki S, Suda T, Toida T, Kashiwagi K, Igarashi K,Higashi K, J. Biol. Chem.,301: 110453, (2025).
  45. Ohira, K., Numata,K., Yoshida, S. Synthesis ofPartially Reduced Biaryls from ThiopheneS,S-Dioxides and Styrenes, Bull. Chem. Soc. Jpn., 98: uoaf052 (2025).
  46. Yasuda, T., Yoshida, S.Selective hydrogenation throughphosphazide formation, RSCAdv., 15: 20350 (2025).
  47. Hiromasa, S., Hamada, M., Orimoto, G., Yoshida, S. Sequentialassembly via Michael addition of 2-(triazolyl)acrylates, Bull. Chem. Soc. Jpn., 98:uoaf061 (2025).
  48. Meng, F., Wang, P., Yang, L.,Yan, J., Giri, A. K., Lee, J., Kusamori, K., Nishikawa, M., Itakura,S., Gu, H., Li, Q., Chen, Z., Yang, Z., Li, D., Cai, Y. Construction ofpH-responsive albumin nanoparticles loaded with baicalin and evaluation oftheir anti-breast cancer activity. Int. J. Biol. Macromol.,322: 146937 (2025).
  49. Hashimoto, M., Itakura,S., Kusamori, K., Yajima, K., Mitsuhashi, S., Hayashi, S., Todo, H.,Nishikawa, M. Therapeutic potential of rose hip-derived nanoparticlesfor psoriatic skin inflammation. ACS Biomater. Sci. Eng., 11:5938-5951 (2025).
  50. Matsumoto, S.,Itakura, S., Minato, J., Hashimoto, M., Obana, S., Kanai, M., Kobayashi,M., Nishikawa, M., Kusamori, K. Cell Observation and Analysiswith a Three-Dimensional Optical Wave Field Microscope. Biosensors,15: 515 (2025).
  51. Itakura, S., Kusamori, K., Nishikawa,M. 非哺乳類由来細胞外小胞の機能とDDSへの応用. 膜, 50: 174-179 (2025).
  52. Li, Q., Meng, F., Yang,L., Díaz García, A. M., Parkhats, M., Lee, J., Kusamori, K., Nishikawa,M., Gu, H., Li, Q., Williams, G. R., Yang, Z., Cai, Y. MetabolicReprogramming of Tumors: Induced Immunosuppression and Therapeutic Prospects ofNanoscale Drug Delivery Systems. Mol. Pharm.,22: 5193-5211. (2025).
  53. Mizutani, A., Kondo, M., Itakura,S., Takamura, H., Hoshino, Y., Nishikawa, M., Kadota, I., Kusamori,K., Tanaka, K. Redox-potential-controlled intermolecular [2 + 2]cycloaddition of styrenes for the regio- and diastereoselective synthesis ofmultisubstituted halogenocyclobutanes. Bull. Chem. Soc. Jpn., 98:uoaf044 (2025).
  54. Li, Q., Meng, F., Xie,M., Nishikawa, M., Kusamori, K., Giri, AK., Yang, L., Li, Qi.,Gu, H., Chen, Z., Yang, Z., Qin, J., Cai, Yu. Folate-targeted pH-sensitivealbumin nanoparticles loaded with Baicalin enhance tamoxifen efficacy andovercome drug resistance in estrogen receptor alpha-positive breast cancer. Int.J. Biol. Macromol., 318: 145-155 (2025).
  55. Jin, J., Kusamori, K.,Yamagata, Y., Itakura, S., Nishikawa, M. Induction of sustainedantibody responses by subcutaneous administration of immunostimulatoryTakumi-shaped CpG DNA hydrogel loaded with Japanese cedar pollen antigen Cryj1in mice. J. Drug Deliv. Sci. Technol., 109: 107011 (2025).
  56. Oshima, N., Kusamori,K., Takasaki, R., Hada, N., Nishikawa, M. Baicalin-inducedhepatocyte toxicity: The critical role of multidrug resistance-associatedprotein 2. Integr. Med. Discov., 9: e25001 (2025).
  57. Narita, I., Todo, H.,Fujiwara, C., Teramae, H., Oshizaka, T., Itakura, S., Komatsu, S.,Takayama, K., Sugibayashi, K. In silico model to predict dermal absorption ofchemicals in finite dose conditions, J. Toxicol. Sci., 50:171-186 (2025).
  58. Tamori S,Matsuda C, Kasai T, Ohno S, Sasaki K, ;Akimoto K. Asymmetric celldivision of ALDH1-positive cancer stem cells generates glycolytic metabolicallydiverse cell populations, Sci Rep. 15(1):13932 (2025).
  59. Zeng Q, TamoriS, Harada T, Application of Graph Attention Network for Breast Cancer Dataand Explanation of Prediction Basis, IEEE Access,13:99183-99191(2025).
  60. Suzuki M, Suzuki T, Nakano Y, Matsumoto K,Manaka H, Komeno M,Tamori S, Sato A, Dohmae N, ;Akimoto K, Miyazaki S, Suda T, Toida T, Kashiwagi K, Igarashi K, Higashi K. Polyaminesstimulate the protein synthesis of the translation initiation factor eIF5A2,participating in mRNA decoding, distinct from eIF5A1, J Biol Chem.301(8):110453(2025). Online ahead of print.
  61. Nagashima Y, Sasaki K, ChiwakiR, Ishii H, Nohata K, MaemuraY, Kasai T, Ozaki A, Tamori S, Ohno S, ;AkimotoK. High Expression of ;PKCζ ;And ;CTNNBIP1 ;IsAssociated With Poor Prognosis in Luminal B BreastCancer, Cancer Genomics Proteomics. ;22(4):538-556(2025).
  62. Nagashima Y, Sasaki K, NohataK, Chiwaki R, Maemura Y,Kasai T, Ozaki A, Tamori S, OhnoS, ;Akimoto K. High Expression of PKCζand ALDH1A3 Is Associated With Poor Prognosisin Luminal B Breast Cance, Anticancer Res.,45(10):4357-4372(2025).
  63. Maemura Y, Ozaki A, ChiwakiR, Enomoto M, Tada Y, Nagashima Y, Ishii H, Nohata K,Kasai T, Okiyama R, Harada Y, TamoriS, Ohno S, Sasaki K, Akimoto K, High p62 and ALDH1A3 reduce the effectiveness ofendocrine therapy in luminal B breast cancer, CancerDiagn. Progn.(2025) in press.
  64. Nohata k, Enomoto M, Ishiyama A, Nagashima y, Okiyama R, Kasai T, TamoriS, Harada Y, Ohno S, Sasaki K, Akimoto K, PKCζ, CTNNBIP1 and ALDH1A3 expression in luminal B breastcancer indicates decreased hormone therapy effectiveness, Cancer Diagn. Progn. (2025)in press.
  65. Yosioka,Y., Yamamoto, S., Kusamori, K.,Nakayama, M., Fujita, H., Goto, A., Iwasaki, S., Nagata, T., Itakura, S., Kusuhara, H., Yokota, T., Hirabayashi, H., Nishikawa, M.Pharmacokinetics and protein binding of cholesterol-conjugated heteroduplexoligonucleotide. J. Control. Release. 380: 787-799 (2025).
  66. Jin, J., Kusamori, K., Tanifuji, T., Yamagata, Y., Itakura, S., Nishikawa,M. Biocompatible DNA hydrogel composed of minimized Takumi-shaped DNAnanostructure exhibits sustained retention after in vivo administration. J.Control. Release., 377: 704-715 (2025).

2024

  1. Takasawa, S., Kimura, K., Miyanaga, M., Uemura, T., Hachisu, M., Miyagawa, S., Ramadan, A., Sukegawa, S., Kobayashi, M., Kimura, S., Matsui, K., Shiroishi, M., Terashita, K., Nishiyama, C., Yashiro, T., Nagata, K., Higami, Y., Arimura, G. The powerful potential of amino acid menthol esters for anti-inflammatory and anti-obesity therapies. Immunology 173:76-92 (2024).
  2. Ando, M., Nagata, K., Takeshita, R., Ito, N., Noguchi, S., Minamikawa, N., Kodama, N., Yamamoto, A., Yashiro, T., Hachisu, M., Ichihara, G., Kishino, S., Yamamoto, M., Ogawa, J., Nishiyama, C. The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling. Front. Immunol. 15:1374425 (2024).
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