Takahashi, Y., Sato, K., Wada, T. Preparation of boranophosphate DNA via the boranophosphotriester method and synthesis of P-modified DNAs from boranophosphate DNA via an acyl phosphite intermediate. Current Protocols in press.
Ikeda, Y., Yamashita, N., Ito, N., Minamikawa, N., Okamura, H., Yashiro, T., Hachisu, M., Aida, M., Yamada, R., Nagata, K., Nishiyama, C. Immunostimulatory effects of Hyndrickxia coaglans SANK70258. Biosci. Biotechnol. Biochem.in press.
Oishi, K., Nakano, N., Ota, M., Inage, E., Izawa, K., Kaitani, A., Ando, T., Hara, M., Ohtsuka, Y., Nishiyama, C., Ogawa, H., Kitaura, J., Okumura, K., Shimizu, T. MHC class II-expressing mucosal mast cells promote intestinal mast cell hyperplasia in a mouse model of food allergy. Allergyin press.
Takahashi, M., Nagata, K., Watanuki, Y., Yamaguchi, M., Ishii, K., Harada, T., Minamikawa, N., Katagiri, M., Zhao, W., Ito, N., Yashiro, T., Nishiyama, C. Kaempferol exerts anti-inflammatory effects by accelerating Treg development via Aryl hydrocarbon receptor-mediated and PU.1/IRF4-dependent transactivation of the Aldh1a2/Raldh2 gene in dendritic cells. Allergy80:896-900 (2025).
Tojima, R., Nagata, K., Ito, N., Ishii, K., Arai, T., Ito, T., Kasakura, K., Nishiyama, C. Roles of C/EBPa, GATA2, TGF-b signaling, and epigenetic regulation in the expression of basophil-specific protease genes. FEBS Lett. 599:777-786 (2025).
Hamada, M., Yoshida, S. Conditional fluorescent changes of azaylides with fluorescent chromophores, Chem. Lett. 54: upaf033 (2025)
Hoshi, Y., Tabata, S., Yoshida, S. Synthesis of α-arylacetophenone derivatives by Grignard reactions and transformations of arynes via C–C bond cleavage. Chem. Commun. 61: 3752 (2025).
Kawada, M., Tabata, S., Hoshi, Y., Yoshida, S. Thioxanthone Synthesis from Thioureas through Double Aryne Insertion into a Carbon=Sulfur Double Bond. Org. Lett. 27: 827 (2025).
Tanaka, T., Tabata, S., Nakamura, K., Hazama, Y., Sakata, Y., Hosoya, T., Yoshida, S. Synthesis of Multisubstituted Naphthalenes through Consecutive Aryne Reactions. Bull. Chem. Soc. Jpn. 98: uoaf001 (2025).
Yasuda, T., Orimoto, G., Yoshida, S. Three-step click assembly using trivalent platforms bearing azido, ethynyl, and fluorosulfonyl groups. Chem. Commun. 61: 2333 (2025).
Hirose, K., Nitto, R., Yokota, S., Kawano, Y., Yamatoya, K., Tabuchi, A., Suzuki, Y., Hanawa, T. Preparing and Characterizing of Xyloglucan Films Containing Tea Extract for Oral Mucositis. ACS Omega 10, 390–399 (2025).
Yoshioka, Y., Yamamoto, S., Kusamori, K., Nakayama, M., Fujita, H., Goto. A., Iwasaki, S., Nagata, T., Itakura, S., Kusuhara, H., Yokota, T., Hirabayashi, H., Nishikawa, M. Pharmacokinetics and protein binding of cholesterol-conjugated heteroduplex oligonucleotide. J. Control. Release 380: 787-799 (2025).
Jin, J., Kusamori, K., Tanifuji, T., Yamagata, Y., Itakura, S., Nishikawa, M. Biocompatible DNA hydrogel composed of minimized Takumi-shaped DNA nanostructure exhibits sustained retention after in vivo administration. J. Control. Release 377: 704-715 (2025). 東京理科大学プレスリリース https://www.tus.ac.jp/today/archive/20250213_0214.html
Kakuta, K., Sakamoto, T., Sato, H., Sato, K., Wada, T. Stereocontrolled Synthesis and NMR Analysis of PB/PO Chimeric Oligonucleotides. R. Soc. Open Sci. in press (2025).
Akita, T. Curative Treatment for COPD Based on Differentiation Induction by Synthetic Retinoid Am80 and Development of Inhalation Powder. YAKUGAKU ZASSHI 145: 1-6 (2025).
2024
Takasawa, S., Kimura, K., Miyanaga, M., Uemura, T., Hachisu, M., Miyagawa, S., Ramadan, A., Sukegawa, S., Kobayashi, M., Kimura, S., Matsui, K., Shiroishi, M., Terashita, K., Nishiyama, C., Yashiro, T., Nagata, K., Higami, Y., Arimura, G. The powerful potential of amino acid menthol esters for anti-inflammatory and anti-obesity therapies. Immunology173:76-92 (2024).
Ando, M., Nagata, K., Takeshita, R., Ito, N., Noguchi, S., Minamikawa, N., Kodama, N., Yamamoto, A., Yashiro, T., Hachisu, M., Ichihara, G., Kishino, S., Yamamoto, M., Ogawa, J., Nishiyama, C. The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling. Front. Immunol.15:1374425 (2024).
Mizobuchi, S., Hirose, K., Ishii, N., Kawano, Y., Hanawa, T. Preparation and characterization of the ground mixture of rebamipide commercial tablets and Hydroxypropyl Cellulose-SSL by ball-milling: Application to the dispersoid of mouthwash suspension. Eur. J. Pharm. Biopharm. 206:114584 (2024).
Nakamura, K., Suzuki, M., Yoshida, S. Synthesis of Thiaphenanthridinones from Sulfinate Esters and 2-Borylanilines. Org. Lett. 26: 9676 (2024).
Yamamoto, C., Numata, K., Suzuki, M., Yoshida, S. Regioselective pyridazine synthesis from tetrazines and alkynyl sulfides. Org. Chem. Front. 11: 6159 (2024).
Pal, K., Singh S., Itakura, S., Hashimoto M., Kusamori, K., Nishikawa, M. Reactive oxygen species augmented polydopamine-chlorin e6 nanosystem for enhanced hemo/photothermal/photodynamic therapy: A synergistic trimodal combination approach in vitro and in vivo. Int. J. Biol. Macromol. 283: 137236 (2024).
Gao, L., Meng, F., Yang, Z., Merchan, M.L., Fernández, L.M., Cao, Y., Kusamori, K., Nishikawa, M., Itakura, S., Chen, J., Huang, X., Ouyang, D., Riester, O., Deigner, H.P., Lai, H., Pedraz, J.L., Ramalingam, M., Cai, Y. Nano-drug delivery system for the treatment of multidrug-resistant breast cancer: Current status and future perspectives. Biomed. Pharmacother. 179:117327 (2024).
Yoshida, Y., Aoki, M., Nagase, K., Marubashi, K., Kojima, H., Itakura, S., Komarsu, S., Sugibayashi, K., Todo, H. Plasmid DNA delivery into the skin via electroporation with a depot-type electrode. Pharmaceutics 16:1219 (2024).
Torigoe, H., Nakayama, S., Shiraishi, T., Sato, K., Hara, R. I., Wada, T. Development of cationic oligodiaminogalactoses specifically binding to duplex RNA, but not to duplex DNA. Thermochimica Acta 738: 179789 (2024).
Yang, Y., Nakayama, K., Okada, S., Sato, K., Wada, T., Sakaguchi, Y., Murayama, A., Suzuki, T., Sakurai, M. ICLAMP: a novel technique to explore adenosine deamination via inosine chemical labeling and affinity molecular purification. FEBS Lett. 598: 1080-1093 (2024).
Nozaki, Y., Suwa, F., Furuya, K., Komeno, M., Hoshino, S., Mizunoe, Y., Higashi, K., Kobayashi, M., Higami, Y. The effects of WWP1 overexpression on the golgi apparatus stress response and proteoglycan production in adipocytes. Scientific Reports. 14(1): 29004-29004 (2024).
Oshima, N., Kusamori, K., Takasaki, R., Takeda, M., Katsurada, Y., Nose, T., Okoshi, K., Nishikawa, M., Hada, N. Scutellaria Root extract-induced hepatocytotoxicity can be controlled by regulating its baicalin content. J. Nat. Med. 78: 978-984 (2024).
Kawato, K., Sato, K., Wada, T. α-Selective Solid-Phase Synthesis of Glycosyl Phosphate Repeating Structure via the Phosphoramidite Method. Chem. Eur. J. e202401226 (2024).
Matsuoka I, Kasai T, Onaga C, Ozaki A, Motomura H, Maemura Y, Tada Y, Mori H, Hara Y, Xiong Y, Sato K, Tamori S, Sasaki K, Ohno S, Akimoto K, Co‑expression of SLC20A1 and ALDH1A3 is associated with poor prognosis, and SLC20A1 is required for the survival of ALDH1‑positive pancreatic cancer stem cells, Oncol Lett. 2024 Jul 5;28(3):426. doi: 10.3892/ol.2024.14558. eCollection 2024 Sep.
Imai, S., Fukano, Y., Niwayama, Y., Tamura, N., Miyoshi, M., Fukuhara, K., Kodaira, H., Iwazaki, N., Yamanaka, Y., Miyazawa, N., Takakusa, H., Kadotsuji, K., Goto, A., Shimada, S., Yoshida, T., Obika, S., Nishikawa, M. Inoue, T. Survey and Consideration for Evaluation of Tissue Distribution and Plasma/Serum Protein Binding of Approved Oligonucleotide Therapeutics. 医薬品医療機器レギュラトリーサイエンス 55(3):208-209 (2024).
Tan, M., Makiguchi, N., Kusamori, K., Itakura, S., Takahashi, Y., Takakura, Y., Nishikawa, M. Tuning CpG motif position in nanostructured DNA for efficient immune stimulation. Biotechnology Journal 19(4):e2300308 (2024).
Sasaki, D., Suzuki, H., Kusamori, K., Itakura, S., Todo, H., Nishikawa, M. Development of rice bran -derived nanoparticles with excellent anti-cancer activity and their application for peritoneal dissemination. Journal of Nanobiotechnology 22:114 (2024).
Akita, T., Shimamura, M., Tezuka, A., Takagi, M., Yamashita, C., GLP-1 derivatives with functional sequences transit and migrate through trigeminal neurons. European Journal of Pharmaceutics and Biopharmaceutics 195: 114176 (2024).
Orimoto, G., Yoshida, S., Iterative click reactions using trivalent platforms for sequential molecular assembly, Chemical Communication, 60: 4545 (2024).
Tabata, S., Yoshida, S., Bromothiolation of Arynes for the Synthesis of 2-Bromobenzenethiol Equivalents, Organic Letters, 26: 3816 (2024).
Kobayashi, A., Tabata, S., Yoshida, S., Highly substituted benzo[b]furan synthesis through substituent migration, Chemical Communication, 60: 4545 (2024). A. Kobayashi, S. Tabata, S. Yoshida*
Kumagai, Y., Kobayashi, A., Nakamura, K., Yoshida, S., Facile Synthesis of Dibenzothiophene S-Oxides from Sulfinate Esters, Chemical Communication, 60: 1611 (2024).
Kanemaru, K., Nagasawa, K., Kunugi, Y., Tanaka, A., Tai, Y., Harada, Y., Nakamura, Y. Epidermal loss of Bcl6 exacerbates MC903-induced atopic dermatitis-like skin inflammation. Biochem. Biophys. Res. Commun. 705:149745 (2024).
Nagata, K., Ando, D., Ashikari, T., Ito, K., Miura, R., Fujigaki, I., Goto, Y., Ando, M., Ito, N., Kawazoe, H., Iizuka, Y., Inoue, M., Yashiro, T., Hachisu, M., Kasakura, K., Nishiyama, C. Butyrate, valerate, and niacin ameliorate anaphylaxis by suppressing IgE-dependent mast cell activation: Roles of GPR109A, PGE2, and epigenetic regulation. J. Immunol. 212:771-784 (2024).