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‚jƒKƒ‰ƒNƒg[ƒX“]ˆΪy‘f(GalT-IjŒ‡‘Ήƒ}ƒEƒX

1) Asano, M., Furukawa, K., Kido, M., Matsumoto, S., Umesaki, Y., Kochibe, N. and Iwakura, Y. Growth retardation and early death of ƒΐ-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells. EMBO J., 16,1850-1857 (1997).

2) Kido, M., Asano, M., Iwakura, Y., Ichinose, M., Miki, K., and Furukawa, K. Presence of polysialic acid and HNK-1 carbohydrate on brain glycoproteins from ƒΐ-1,4-galactosyltransferase-knockout mice. Biochem. Biophys. Res. Commun., 245, 860-864 (1998).

3) Kotani, N., Asano, M., Iwakura, Y., and Takasaki, S. Impaired b1, 4-galactosylation of core 2 O-glycans in erythrocytes of ƒΐ1, 4-galactosyl-transferase knockout mice. Biochem. Biophys. Res. Commun., 260, 94-98 (1999).

4) Kido, M., Asano, M., Iwakura, Y., Ichinose, M., Miki, K., and Furukawa, K. Normal levels of serum glycoproteins maintained in ƒΐ-1, 4-galactosyltransferase I-knockout mice. FEBS Letters, 464, 75-79 (1999).

5) Kido, M., Asano, M., Iwakura, Y., Ichinose, M., Miki, K., and Furukawa, K. Presence of a higher molecular weight ƒΐ-1, 4-galactosyltransferase in mouse liver. Acta Histochem. Cytochem., 33, 215-221 (2000).

6) Kotani, N., Asano, M., Iwakura, Y., and Takasaki, S. Knockout of mouse ƒΐ1,4-galactosyltransferase-1 gene results in a dramatic shift of outer chain moieties of N-glycans from type 2 to type 1 chains in hepatic membrane and plasma glycoproteins. Biochem J., 357, 827-834 (2001).

7) Asano, M., Nakae, S., Kotani, N., Shirafuji, N., Nambu, A., Hashimoto, N., Kawashima, H., Hirose, M., Miyasaka, M., Takasaki, S., and Iwakura, Y. Impaired selectin ligand biosynthesis and reduced inflammatory responses in ƒΐ-1,4-galactosyltransferase-I-deficient mice. Blood, 102, 1678-1685 (2003).

8) Kotani, N., Asano, M., Inoue, N., Iwakura, Y., and Takasaki, S. Polylactosamine synthesis and branch formation of N-glycans in ƒΐ1,4-galactosyltransferase-1-deficient mice. Arch. Biochem. Biophys., 426, 258-265 (2004).

‚‚jEph A2 Œ‡‘Ήƒ}ƒEƒX

1) Naruse-Nakajima, C., Asano, M., and Iwakura, Y. Involvement of EphA2 in the formation of the tail notochord via interaction with ephrinA1. Mecha. Develop., 102, 95-105 (2001).

2) Irie, N., Takada, Y., Watanabe, Y., Matsuzaki, Y., Naruse, C., Asano, M., Iwakura, Y., Suda, T., and Matsuo, K. Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis. J. Biol. Chem., 284, 14637-14644 (2009).

‚ƒjSix-‚SŒ‡‘Ήƒ}ƒEƒX

1) Ozaki, H., Watanabe, Y., Takahashi, K., Kitamura, K., Tanaka, A., Urase, K., Momoi., T., Sudo, K., Sakagami, J., Asano, M., Iwakura, Y., and Kawakami, K. Six-4, a putative myogenin gene regulator, is not essential for mouse embryonal development. Mol. Cell. Biol., 21, 3343-3350 (2001).

‚„jMeltrinƒΏŒ‡‘Ήƒ}ƒEƒX

1) Kurisaki, T., Masuda, A., Sudo, K., Sakagami, J., Higashiyama, S., Matsuda, Y., Nagabukuro, A., Nabeshima, Y., Asano, M., Iwakura, Y. and Sehara-Fujisawa, A. Phenotypic analysis of MeltrinƒΏ (ADAM12)-deficient mice: involvement of MeltrinƒΏ in adipogenesis and myogenesis. Mol. Cell. Biol., 23, 55-61 (2003).

‚…jMeltrinƒΐŒ‡‘Ήƒ}ƒEƒX

1) Kurohara, K., Komatsu, K., Kurisaki, T., Masuda, A., Irie, N., Asano, M., Sudo, K., Nabeshima, Y., Iwakura, Y., Sehara-Fujisawa, A. Essential roles of Meltrin ƒΐ (ADAM19) in heart development. Dev. Biol., 267, 14-28 (2004).

‚†jFliceŒ‡‘Ήƒ}ƒEƒX

1) Sakamaki, K., Inoue, T., Asano, M., Sudo, K., Kazama, H., Sakagami, J., Sakata, S., Ozaki, M., Nakamura, S., Toyokuni, S., Osumi, N., Iwakura, Y. and Yonehara, S. Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart. Cell Death Differ., 9, 1196-1206 (2002).

‚‡jSix-1Œ‡‘Ήƒ}ƒEƒX

1) Ozaki, H., Nakamura, K., Funahashi, JI., Ikeda, K., Yamada, G., Tokano, H., Okamura, HO., Kitamura, K., Muto, S., Kotaki, H., Sudo, K., Horai, R., Iwakura, Y., and Kawakami, K. Six1 controls patterning of the mouse otic vesicle. Development, 131, 551-562 (2004).

‚ˆjSix-1/Six-4Œ‡‘Ήƒ}ƒEƒX

1) Konishi, Y., Ikeda, K., Iwakura, Y., and Kawakami, K. Six1 and Six4 promote survival of sensory neurons during early trigeminal gangliogenesis. Brain Res., 1116, 93-102 (2006).

‚‰jOvol2Œ‡‘Ήƒ}ƒEƒX

1) Unezaki, S., Horai, R., Sudo, K., Iwakura, Y., and Ito, S. Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice. Genes Cells, 12, 773-785 (2007).

‚ŠjcPGESŒ‡‘Ήƒ}ƒEƒX

1) Nakatani, Y., Hokonohara, Y., Kakuta, S., Sudo, K., Iwakura, Y., and Kudo, I. Knockout mice lacking cPGES/p23, a constitutively expressed PGE₂ synthetic enzyme, are peri-natally lethal. Biochem. Biophys. Res. Commun., 362, 387-392 (2007).

kjKidŒ‡‘Ήƒ}ƒEƒX

1) Ohsugi, M., Adachi, K., Horai, R., Kakuta, S., Sudo, K., Kotaki, H., Tokai-Nishizumi, N., Sagara, H., Iwakuta, Y., and Yamamoto, T. Kid-Mediated Chromosome Compaction Ensures Proper Nuclear Envelope Formation. Cell, 132, 771-782 (2008).

ljGƒΐ1Œ‡‘Ήƒ}ƒEƒX

1) Okae, H., and Iwakura, Y. Neural tube defects and impaired neural progenitor cell proliferation in Gƒΐ1-deficient mice. Dev. Dyn., 239, 1089-1101 (2010).