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‚jPTP-ƒΒŒ‡‘Ήƒ}ƒEƒX

1) Uetani, N., Kato, K., Ogura, K., Mizuno, H., Kawano, K., Mikoshiba, K., Yakura, H., Asano, M., and Iwakura, Y. Impaired learning with enhanced hippocampal long-term potentiation in PTPƒΒ-deficient mice. EMBO J., 19, 2775-2785 (2000).

2) Uetani, N., Chagnon, MJ., Kennedy, TE., Iwakura, Y., and Tremblay, ML. Mammalian Motoneuron Axon Targeting Requires Receptor Protein Tyrosine Phosphatases ƒΠ and ƒΒ. J. Neurosci., 26, 5872-5880 (2006).

‚‚jTag-1Œ‡‘Ήƒ}ƒEƒX

1) Fukamauchi, F., Aihara, O., Wang, Y. J., Akasaka, K., Takeda, Y., Horie, M., Kawano, H., Sudo, K., Asano, M., Watababe, K., and Iwakura, Y. TAG-1-deficient mice have marked elevation of adenosine A1 receptors in the hippocampus. Biochem. Biphys. Res. Commun., 281, 220-226 (2001).

2) Traka, M., Goutebroge, L., Denisenko, N., Bessa, M., Nifli, A., Havaki, S., Iwakura, Y., Fukamauchi, F., Watanabe, K., Soliven, B., Girault, J. A., and Karagogeos, D. Association of Tag-1 with Caspr 2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers. J. Cell. Biol., 162, 1161-1172 (2003).

‚ƒjškŠoŽσ—e‘ΜGFPƒmƒbƒNƒCƒ“ƒ}ƒEƒX

1) Serizawa, S., Ishii, T., Nakatani, H., Tsuboi, A., Nagawa, F., Asano, M., Sudo, K., Sakagami, J., Sakano, H., Ijiri, T., Matsuda, Y., Suzuki, M., Yamamori, T., Iwakura, Y., and Sakano, H. Mutually exclusive expression of odorant receptor transgenes. Nature Neuroscience, 3, 687-693 (2000).

2) Ishii, T., Serizawa, S., Kohda, A., Nakatani, H., Shiroishi, T., Okumura, K., Iwakura, Y., Nagawa, F., Tsuboi, A., and Sakano, H. Projection of three subsets of olfactory neurons expressing the odorant receptor transgene and the two cognate endogenous alleles. Genes to Cell, 6, 71-78 (2001).

d) HNK-1Œ‡‘Ήƒ}ƒEƒX

1) Yamamoto, S., Oka, S., Inoue, M., Shimuta, M., Manabe, T., Takahashi, H., Miyamoto, M., Asano, M., Sakagami, J., Sudo, K., Iwakura, Y., and Kawasaki, T. Mice deficient in nervous system-specific carbohydrate epitope HNK-1 exhibit impaired synaptic plasticity and spatial learning. J. Biol. Chem., 277, 27227-27231 (2002).

e) NB-2Œ‡‘Ήƒ}ƒEƒX

1) Li, H., Takeda, Y., Niki, H., Ogawa, J., Kobayashi, S., Kai, N., Akasaka, K., Asano, M., Sudo, K., Iwakura, Y., and Watanabe, K. Aberrant responses to acoustic stimuli in mice deficient for neural recognition molecule NB-2. Eur. J. Neurosci., 17, 483-490 (2003).

‚†) NB-3Œ‡‘Ήƒ}ƒEƒX

1) Takeda, Y., Akasaka, K., Lee, S., Kobayashi, S., Kawano, H., Murayama, S., Takahashi, N., Hashimoto, K., Kano, M., Asano, M., Sudo, K., Iwakura, Y., and Watanabe, K. Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contaction/F3 subgroup. J. Neurobiol., 56, 252-265 (2003).

‚‡jAls2Œ‡‘Ήƒ}ƒEƒX

1) Hadano, S., Benn, SC., Kakuta, S., Otomo, A., Sudo, K., Kunita, R., Suzuki-Utsunomiya, K., Mizumura, H., Shefner, JM., Cox, GA., Iwakura, Y., Brown, RH. Jr., and Ikeda, JE. Mice Deficient in the Rab5 Guanine Nucleotide Exchange Factor ALS2/alsin Exhibit Age-Dependent Neurological Deficits and Altered Endosome Trafficking. Hum. Mol. Genet., 15, 233-250 (2006).

2) Hadano, S., Yoshii, Y., Otomo, A., Kunita, R., Suzuki-Utsunomiya, K., Pan, L., Kakuta, S., Iwasaki, Y., Iwakura, Y., and Ikeda J.E. Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice. Neurosci. Res., 68, 131-136 (2010).

‚ˆjNR2B Y1472FƒmƒbƒNƒCƒ“ƒ}ƒEƒX

1) Nakazawa, T., Komai, S., Watabe, AM., Kiyama, Y., Fukaya, M., Arima-Yoshida, F., Horai, R., Sudo, K., Ebine, K., Delawary, M., Goto, J., Umemori, H., Tezuka, T., Iwakura, Y., Watanabe, M., Yamamoto, T., and Manabe, T. NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity. EMBO J., 25, 2867-2877 (2006).

‚‰jDok7Œ‡‘Ήƒ}ƒEƒX

1) Okada, K., Inoue, A., Okada, M., Murata, Y., Kakuta, S., Jigami, T., Kubo, S., Shiraishi, H., Eguchi, K., Motomura, M., Akiyama, T., Iwakura, Y., Higuchi, O., and Yamanashi, Y. The Muscle Protein Dok-7 Is Essential for Neuromuscular Synaptogenesis. Science, 312, 1802-1805 (2006).

2) Inoue, A., Setoguchi, K., Matsubara, Y., Okada, K., Sato, N., Iwakura, Y., Higuchi, O., and Yamanashi, Y. Dok-7 Activates the Muscle Receptor Kinase MuSK and Shapes Synapse Formation. Sci. Signaling, 2, ra7 (2009).

‚Šj20ƒΏ-HSDŒ‡‘Ήƒ}ƒEƒX

1) Ishida, M., Choi, JH., Hirabayashi, K., Matsuwaki, T., Suzuki, M., Yamanouchi, K., Horai, R., Sudo, K., Iwakura, Y., and Nishihara, M. Reproductive Phenotypes in Mice with Targeted Disruption of the 20ƒΏ-Hydroxysteroid Dehydrogenase Gene. J. Reprod. Dev., 53, 499-508 (2007).

kjGranulinŒ‡‘Ήƒ}ƒEƒX

1) Kayasuga, Y., Chiba, S., Suzuki, M., Kikusui, T., Matsuwaki, T., Yamanouchi, K., Kotaki, H., Horai, R., Iwakura, Y., and Nishihara, M. Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene. Behav. Brain Res., 185, 110-118 (2007).

ljPTPMEGŒ‡‘Ήƒ}ƒEƒX

1) Kina, S., Tezuka, T., Kusakawa, S., Kishimoto, Y., Kakizawa, S., Hashimoto, K., Ohsugi, M., Kiyama, Y., Horai, R,. Sudo, K., Kakuta, S., Iwakura, Y., Iino, M., Kano, M., Manabe, T., and Yamamoto, T. Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression. Eur. J. Neurosci., 26, 2269-2278 (2007).

mjNR2A Y1325FƒmƒbƒNƒCƒ“ƒ}ƒEƒX

1) Taniguchi, S., Nakazawa, T., Tanimura, A., Kiyama, Y., Tezuka, T., Watabe, A.M., Katayama, N., Yokoyama, K., Inoue, T., Izumi-Nakaseko, H., Kakuta, S., Sudo, K., Iwakura, Y., Umemori, H., Inoue, T., Murphy, N.P., Hashimoto, K., Kano, M., Manabe, T., and Yamamoto, T. Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. EMBO J., 28, 3717-3729 (2009).